Evidence map›Paper›PMID 34963729›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2021

Early Experience of High-dose Intravenous

Parth Sudhendu Patel, Sudhendu Patel, Vidhi Shah, Varsha Aswani, Mahendra Narwaria

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in immunology · 2024
    Review
  3. Effects ofInternational journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Parth Sudhendu PatelDepartment of Critical Care, Bombay Hospital, Institute of Medical Sciences, Ahmedabad, Gujarat, India.ORCID https://orcid.org/0000-0002-0061-5721
Sudhendu PatelDepartment of Medicine, Sterling Hospital, Ahmedabad, Gujarat, India.
Vidhi ShahDepartment of Medicine, Sterling Hospital, Ahmedabad, Gujarat, India.
Varsha AswaniDepartment of Surgery, VS Hospital, Ahmedabad, Gujarat, India.ORCID https://orcid.org/0000-0002-8495-0227
Mahendra NarwariaDepartment of Surgery, Asian Bariatrics Hospital, Ahmedabad, Gujarat, India.ORCID https://orcid.org/0000-0002-0611-1567
Sterling Hospitals · INAhmedabad Civil Hospital · INCare Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune dysregulation is one of the main reasons for mortality and morbidity in coronavirus disease 2019 (COVID-19). Mycobacterium w (Mw) is recently approved for gram-negative sepsis. Moreover, it is also found effective in COVID-19 patients in previous studies. The traditional route of administration for Mw is intradermal, which has a limitation of administering 0.1 mL per injection and local injection site reaction. Intravenous (IV) administration of Mw has not been explored in COVID-19. We report the retrospective analysis of six critically ill COVID-19 patients who received Mw (IV). PATIENTS AND

methodsAt baseline, all patients in this case series required O

resultsAfter Mw administration, gradual improvement in O

conclusionUse of 0.6 mL Mw by IV route in this case series was associated with decreased O HOW TO CITE THIS ARTICLE: Patel PS, Patel S, Shah V, Aswani V, Narwaria M. Early Experience of High-dose Intravenous

Indexed as

COVID-19Immune dysregulationImmunomodulatorMycobacterium w

Identifiers

PMID34963729
PMCPMC8664032
OpenAlexW3198817718

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.