Evidence map›Paper›PMID 34963680›Full record

ArticleScientific reports2021

A single-agent extension of the SIR model describes the impact of mobility restrictions on the COVID-19 epidemic.

Matteo Paoluzzi, Nicoletta Gnan, Francesca Grassi, Marco Salvetti, Nicola Vanacore, Andrea Crisanti

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matteo PaoluzziDepartament de Física de la Matèria Condensada, Universitat de Barcelona, C. Martí Franquès 1, 08028, Barcelona, Spain. matteopaoluzzi@ub.edu.
Nicoletta GnanCNR-ISC, Institute for Complex Systems UOS "Sapienza", Piazzale A. Moro 2, 00185, Rome, Italy.
Francesca GrassiDepartment of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.
Marco SalvettiDepartment of Neurosciences, Mental Health and Sensory Organs, Sapienza University of Rome, Rome, Italy.
Nicola VanacoreNational Center for Disease Prevention and Health Promotion, Istituto Superiore di Sanità, Rome, Italy.
Andrea CrisantiCNR-ISC, Institute for Complex Systems UOS "Sapienza", Piazzale A. Moro 2, 00185, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mobility restrictions are successfully used to contain the diffusion of epidemics. In this work we explore their effect on the epidemic growth by investigating an extension of the Susceptible-Infected-Removed (SIR) model in which individual mobility is taken into account. In the model individual agents move on a chessboard with a Lévy walk and, within each square, epidemic spreading follows the standard SIR model. These simple rules allow to reproduce the sub-exponential growth of the epidemic evolution observed during the Covid-19 epidemic waves in several countries and which cannot be captured by the standard SIR model. We show that we can tune the slowing-down of the epidemic spreading by changing the dynamics of the agents from Lévy to Brownian and we investigate how the interplay among different containment strategies mitigate the epidemic spreading. Finally we demonstrate that we can reproduce the epidemic evolution of the first and second COVID-19 waves in Italy using only 3 parameters, i.e , the infection rate, the removing rate, and the mobility in the country. We provide an estimate of the peak reduction due to imposed mobility restrictions, i. e., the so-called flattening the curve effect. Although based on few ingredients, the model captures the kinetic of the epidemic waves, returning mobility values that are consistent with a lock-down intervention during the first wave and milder limitations, associated to a weaker peak reduction, during the second wave.

Indexed as

Models, TheoreticalMovementCOVID-19EpidemicsHumansItalySARS-CoV-2

Identifiers

PMID34963680
PMCPMC8714823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.