Evidence map›Paper›PMID 34963479›Full record

ReviewJournal of nanobiotechnology2021

Preparation, toxicity reduction and radiation therapy application of gold nanorods.

Lina Xie, Xujia Zhang, Chengchao Chu, Yingqi Dong, Tianzi Zhang, Xinyue Li, Gang Liu, Wen Cai, Suxia Han

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Assembling AuJournal of nanobiotechnology · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Pharmaceutics · 2023
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lina XieDepartment of Radiation Oncology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Xujia ZhangInstitute of Medical Engineering, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Chengchao ChuEye Institute of Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.
Yingqi DongInstitute of Medical Engineering, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Tianzi ZhangInstitute of Medical Engineering, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Xinyue LiDepartment of Radiation Oncology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Gang LiuState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Wen CaiInstitute of Medical Engineering, School of Basic Medical Sciences, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China. caiwen2016@xjtu.edu.cn.
Suxia HanDepartment of Radiation Oncology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China. shan87@mail.xjtu.edu.cn.
Xi'an Jiaotong University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNXiamen University · CN

Funding

China Postdoctoral Science Foundation 2019T120924National Natural Science Foundation of China 82071975the Innovation Capacity Support Plan of Shaanxi Province 2018TD002
6 · The paper itself

Abstract

Gold nanorods (GNRs) have a broad application prospect in biomedical fields because of their unique properties and controllable surface modification. The element aurum (Au) with high atomic number (high-Z) render GNRs ideal radiosensitive materials for radiation therapy and computed tomography (CT) imaging. Besides, GNRs have the capability of efficiently converting light energy to heat in the near-infrared (NIR) region for photothermal therapy. Although there are more and more researches on GNRs for radiation therapy, how to improve their biocompatibility and how to efficiently utilize them for radiation therapy should be further studied. This review will focuse on the research progress regarding the preparation and toxicity reduction of GNRs, as well as GNRs-mediated radiation therapy.

Indexed as

RadiotherapyAnimalsGoldHumansHyperthermia, InducedNanotubesPhotosensitizing AgentsPhotothermal TherapyGoldPhotosensitizing AgentsGold nanorods (GNRs)PreparationRadiation sensitizationRadiation therapyToxicity reduction

Identifiers

PMID34963479
PMCPMC8715590
OpenAlexW4200239840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.