Evidence map›Paper›PMID 34963133›Full record

ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2022

Variability in endoscopic assessment of Nissen fundoplication wrap integrity and hiatus herniation.

Erin J Song, Rena Yadlapati, Joan W Chen, Alice Parish, Matthew J Whitson, Karthik Ravi, Amit Patel, Dustin A Carlson, Abraham Khan, Donna Niedzwiecki and 1 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Erin J SongDepartment of Medicine, Duke University, Durham, NC, USA.
Rena YadlapatiDivision of Gastroenterology, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-7872-2033
Joan W ChenDivision of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.
Alice ParishDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
Matthew J WhitsonDivision of Gastroenterology, Zucker School of Medicine at Hofstra-Northwell, Manhasset, NY, USA.
Karthik RaviDivision of Gastroenterology, Mayo Clinic, Rochester, MN, USA.
Amit PatelDivision of Gastroenterology, Duke University, Durham, NC, USA.ORCID 0000-0001-7214-5901
Dustin A CarlsonDivision of Gastroenterology, Northwestern University, Chicago, IL, USA.
Abraham KhanDivision of Gastroenterology, New York University-Langone Health, New York, NY, USA.
Donna NiedzwieckiDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
David A LeimanDivision of Gastroenterology, Duke University, Durham, NC, USA.ORCID 0000-0001-6350-3906
Duke University · USHofstra University · USMayo Clinic in Arizona · USNorthwestern University · USNYU Langone Health · USUniversity of California San Diego · USUniversity of Michigan · US

Funding

Mechanism Guided Therapy for Laryngopharyngeal RefluxK23DK125266 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YADLAPATI, RENA HIREN · 2021 to 2025
$963k
NIDDK NIH HHS K23 DK125266
6 · The paper itself

Abstract

backgroundUpper endoscopy (EGD) is frequently performed in patients with esophageal complaints following anti-reflux surgery such as fundoplication. Endoscopic evaluation of fundoplication wrap integrity can be challenging. Our primary aim in this pilot study was to evaluate the accuracy and confidence of assessing Nissen fundoplication integrity and hiatus herniation among gastroenterology (GI) fellows, subspecialists, and foregut surgeons.

methodsFive variations of post-Nissen fundoplication anatomy were included in a survey of 20 sets of EGD images that was completed by GI fellows, general GI attendings, esophagologists, and foregut surgeons. Accuracy, diagnostic confidence, and inter-rater agreement across providers were evaluated.

resultsThere were 31 respondents in the final cohort. Confidence in pre-survey diagnostics significantly differed by provider type (mean confidence out of 5 was 1.8 for GI fellows, 2.7 for general GI attendings, 3.6 for esophagologists, and 3.6 for foregut surgeons, P = 0.01). The mean overall accuracy was 45.9%, which significantly differed by provider type with the lowest rate among GI fellows (37%) and highest among esophagologists (53%; P = 0.01). The accuracy was highest among esophagologists across all wrap integrity variations. Inter-rater agreement was low across wrap integrity variations (Krippendorf's alpha <0.30), indicating low to no agreement between providers.

conclusionIn this multi-center survey study, GI fellows had the lowest accuracy and confidence in assessing EGD images after Nissen fundoplication, whereas esophagologists had the highest. Diagnostic confidence varied considerably and inter-rater agreement was poor. These findings suggest experience may improve confidence, but highlight the need to improve the evaluation of fundoplication wraps.

Indexed as

Gastroesophageal RefluxLaparoscopyFundoplicationGastroscopyHumansPilot Projectsanti-reflux surgeryendoscopygastroesophageal reflux diseaseNissen fundoplicationtrainees

Identifiers

PMID34963133
PMCPMC9118466
OpenAlexW4200107843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.