Evidence map›Paper›PMID 34962345›Full record

ArticleThe Kaohsiung journal of medical sciences2022

Astragalus polysaccharide alleviated hepatocyte senescence via autophagy pathway.

Ting Yao, Jin-Mei Chen, Le-Er Shen, Yong-Sheng Yu, Zheng-Hao Tang, Guo-Qing Zang, Yi Zhang, Xiao-Hua Chen

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
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  6. Review
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  8. Review
  9. Recent efficacy and long-term survival ofWorld journal of clinical oncology · 2024
    Article
  10. Review
  11. Protective Effects and Mechanisms of Esculetin against HMolecules (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Study on the Mechanism of Radix Astragali against Renal Aging Based on Network Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ting YaoDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.ORCID https://orcid.org/0000-0003-0132-8027
Jin-Mei ChenDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Le-Er ShenDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yong-Sheng YuDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Zheng-Hao TangDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Guo-Qing ZangDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yi ZhangDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Xiao-Hua ChenDepartment of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Shanghai Jiao Tong University · CN

Funding

National Natural Science Foundation of China 81770589
6 · The paper itself

Abstract

Aging is characterized by inevitable organ function decline over time, with consequent body deterioration and increased susceptibility to death. Astragalus polysaccharide (APS) has been reported to have anti-oxidative, anti-apoptotic, and anti-inflammatory properties. We investigated the potential protective effects of APS on hydrogen peroxide (H

Indexed as

AMP-Activated Protein KinasesAstragalus PlantAnimalsApoptosisAutophagyHepatocytesMammalsMiceMice, Inbred C57BLPolysaccharidesSignal TransductionTOR Serine-Threonine KinasesAMP-Activated Protein KinasesPolysaccharidesTOR Serine-Threonine KinasesAMPKAstragalus polysaccharideautophagycell deathhepatocyte senescence

Identifiers

PMID34962345
PMCPMC11896509
OpenAlexW4200589857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.