ReviewThe journal of obstetrics and gynaecology research2022
The giant steps in surgical downsizing toward a personalized treatment of vulvar cancer.
Review in The journal of obstetrics and gynaecology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 48 citations in OpenAlex.
- A Large Vulvar Acrochordon in an 80-Year-Old Woman: A Neglected Hanging Lesion.Clinical case reports · 2025Article
- Prognostic Factors and Quality of Life in Vulvar Cancer Patients: 12-Year Results from a Eastern European Center.Journal of personalized medicine · 2025Article
- Fatal Progression of Vulvar Cancer in Pregnancy: A Case Report on Delayed Intervention.The American journal of case reports · 2025Article
- Symptom Experience After Surgical Treatment for Vulvar Cancer-A Scoping Review.Scandinavian journal of caring sciences · 2025Article
- Case Report: Diagnostic challenges in differentiated-type vulvar intraepithelial neoplasia.Frontiers in oncology · 2025Article
- Article
- Editorial: Diagnosis and treatment of vulvar cancer.Frontiers in oncology · 2025Article
- Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma.Current oncology (Toronto, Ont.) · 2024Article
- Patterns of care for vulvar cancer and insights from revised FIGO staging: a retrospective study.World journal of surgical oncology · 2024Observational
- Overall survival associated with surgery, radiotherapy, and chemotherapy in metastatic vulvar cancer: A retrospective cohort study based on the SEER database.Cancer pathogenesis and therapy · 2024Article
- Is there a role for platelet rich plasma injection in vulvar lichen sclerosus? A self-controlled pilot study.Archives of gynecology and obstetrics · 2024Article
- Treatment of vulvar cancer recurrence with electrochemotherapy: a case-control study.Acta oncologica (Stockholm, Sweden) · 2024Article
- WNL we never looked: vulvar carcinoma incidence after screening cutoff.International journal of women's dermatology · 2024Article
- Vulvar Hidradenoma Papilliferum.International journal of general medicine · 2024Article
- The Importance of p16 and p53 Immunohistochemical Staining in Diagnosing Vulvar Lichen Simplex Chronicus Mimicking Vulvar Intraepithelial Neoplasia with False-Positive Human Papillomavirus Type 66.International journal of women's health · 2024Article
- Atypical Vaginal Aggressive Angiomyxoma in a Virgin: A Case Report from South Jordan.International journal of women's health · 2024Article
- Review effects of radiation treatment on HPV-related vulvar cancer: a meta-analysis and systematic review.Frontiers in oncology · 2024Review
- Effect of known pathological risk factors on the incidence of metastatic lymph nodes and survival in early-stage vulvar cancer: SEER analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2024Article
- Exploring the potential prompting role of cervical human papilloma virus detection in vulvar lesions: a cross-sectional study in China.Frontiers in oncology · 2024Article
- Outcomes and prognostic factors of surgically treated extramammary Paget's disease of the vulva.Journal of gynecologic oncology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present article aims to highlight the importance of changes of personalized surgical treatment for vulvar cancer. Current international literature regarding surgical treatment of vulvar cancer was evaluated. This included several studies and systematic reviews. Radical surgery approach, such as en bloc resection, was the first therapeutic option and the standard care for many years, even if burdened with a high complication rate and frequently disfiguring. Taussing and Way introduced radical vulvectomy approach with en bloc bilateral inguinal-femoral lymphadenectomy; modified radical vulvectomy was developed, with a wide radical excision of the primary tumor. The role of inguinofemoral lymphadenectomy (mono or bilateral) changed in the years too, particularly with the advent of SLN biopsy as minimally invasive surgical approach for lymph node staging, in patients with unifocal cancer <4 cm, without suspicious groin nodes. More personalized and conservative surgical approach, consisting of wide local or wide radical excisions, is necessary to reduce complications as lymphedema or sexual disfunction. The optimal surgical management of vulvar cancer needs to consider dimensions, staging, depth of invasion, presence of carcinoma at the surgical margins of resection and grading, with the goal of making the treatment as individualized as possible.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.