Evidence map›Paper›PMID 34962215›Full record

ArticleDrug delivery2022

Folate-functionalized SMMC-7721 liver cancer cell membrane-cloaked paclitaxel nanocrystals for targeted chemotherapy of hepatoma.

Wenwen Shen, Shuke Ge, Xiaoyao Liu, Qi Yu, Xue Jiang, Qian Wu, YuChen Tian, Yu Gao, Ying Liu, Chao Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenwen ShenPharmacy School, Jinzhou Medical University, Jinzhou, China.
Shuke GeDepartment of Emergency Management, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, China.
Xiaoyao LiuPharmacy School, Jinzhou Medical University, Jinzhou, China.
Qi YuPharmacy School, Jinzhou Medical University, Jinzhou, China.
Xue JiangPharmacy School, Jinzhou Medical University, Jinzhou, China.
Qian WuPharmacy School, Jinzhou Medical University, Jinzhou, China.
YuChen TianDepartment of Medical Oncology, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Yu GaoDepartment of Medical Oncology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Ying LiuPharmacy School, Jinzhou Medical University, Jinzhou, China.
Chao WuPharmacy School, Jinzhou Medical University, Jinzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we prepared a folic acid-functionalized SMMC-7721 liver cancer cell membrane (CM)-encapsulated paclitaxel nanocrystals system (FCPN) for hepatoma treatment. Transmission electron microscopy (TEM) characterization showed that FCPN was irregular spherical shapes with a particle size larger than 200 nm and a coated thickness of approximately 20 nm. In an

Indexed as

AnimalsAntineoplastic Agents, PhytogenicBiomimeticsCarcinoma, HepatocellularCell Line, TumorCell MembraneCell SurvivalDrug CarriersDrug LiberationFemaleFolic AcidHumansLiver NeoplasmsMiceMice, Inbred BALB CMice, NudeAntineoplastic Agents, PhytogenicDrug CarriersFolic AcidPaclitaxelPolyethylene Glycolsfolate functionalizednanocrystalPaclitaxelSMMC-7721 liver cancer cell membranetargeted therapy

Identifiers

PMID34962215
PMCPMC8725828

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.