Evidence map›Paper›PMID 34962186›Full record

ArticleDrug delivery2022

Carbopol emulgel loaded with ebastine for urticaria: development, characterization,

Barkat Ali Khan, Arshad Ali, Khaled M Hosny, Abdulrahman A Halwani, Alshaimaa M Almehmady, Muhammad Iqbal, Waleed S Alharbi, Walaa A Abualsunun, Rana B Bakhaidar, Samar S A Murshid and 1 more

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. Article
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  7. Encapsulation ofGels (Basel, Switzerland) · 2023
    Article
  8. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Barkat Ali KhanDrug Delivery and Cosmetic Lab (DDCL), Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan.
Arshad AliDrug Delivery and Cosmetic Lab (DDCL), Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan.
Khaled M HosnyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0002-4904-1378
Abdulrahman A HalwaniDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Alshaimaa M AlmehmadyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Muhammad IqbalDrug Delivery and Cosmetic Lab (DDCL), Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan.
Waleed S AlharbiDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Walaa A AbualsununDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Rana B BakhaidarDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Samar S A MurshidDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Muhammad Khalid KhanDrug Delivery and Cosmetic Lab (DDCL), Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan.
King Abdulaziz University · SAGomal University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urticaria affects all age groups of a population. It is triggered by allergens in foods, insect bites, medications, and environmental conditions. Urticaria is characterized by itching, a burning sensation, wheals and flares, erythema, and localized edema. The aim of this study was to develop a polymeric dosage form of ebastine using Carbopol 940 and mixture of span and tween. The emulsion was prepared, the gelling agent was added and the desired emulgel loaded with active drug was formulated. The formulations were subjected to physical stability, pH, viscosity, spreadability, drug content analysis, thermal analysis,

Indexed as

Acrylic ResinsAdministration, CutaneousAnimalsButyrophenonesChemistry, PharmaceuticalDisease Models, AnimalDrug CarriersDrug LiberationDrug StabilityEmulsionsGelsHistamine H1 AntagonistsHydrogen-Ion ConcentrationMalePiperidinesRabbitsAcrylic ResinsButyrophenonescarboxypolymethyleneDrug CarriersebastineEmulsionsGelsHistamine H1 AntagonistsPiperidinesanti-allergyCarbopolebastineemulgelUrticaria

Identifiers

PMID34962186
PMCPMC8725930
OpenAlexW4200502314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.