ArticleJPEN. Journal of parenteral and enteral nutrition2022
High neutrophil-to-lymphocyte ratio at intensive care unit admission is associated with nutrition risk in patients with COVID-19.
Article in JPEN. Journal of parenteral and enteral nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Prevalence of disease related malnutrition assessed by NRS2002, STAMP, MNA-SF, one-step and two-step GLIM at admission and discharge: A systematic review and meta-analysis.Asia Pacific journal of clinical nutrition · 2026Pooled it
- Risk of Malnutrition in Hospitalized COVID-19 Patients: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Development and external validation of a prediction model for major adverse kidney events within 30 days in sepsis associated acute kidney injury: a multi-center retrospective clinical study.BMC medical informatics and decision making · 2026Article
- Why should lymphocytes immune profile matter in sepsis?World journal of critical care medicine · 2025Review
- Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes: a prospective cohort study.BMC endocrine disorders · 2024Article
- Evaluation of hematological changes and immune response biomarkers as a prognostic factor in critical patients with COVID-19.PloS one · 2024Article
- Nutritional risk and a high NRS2002 score are closely related to disease progression and poor prognosis in patients with COVID-19.Frontiers in nutrition · 2023Article
- High neutrophil-to-lymphocyte ratio at intensive care unit admission is associated with nutrition risk in patients with COVID-19.JPEN. Journal of parenteral and enteral nutrition · 2022Article
- COVID-19 and liver dysfunction: What nutritionists need to know.World journal of gastroenterology · 2022Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation plays a crucial role in nutrition status and can be useful in early nutrition risk screening of patients during the coronavirus disease 2019 (COVID-19) pandemic. Thus, this study aimed to assess the association between systemic inflammatory markers and nutrition risk tools in intensive care unit (ICU) patients with COVID-19.
methodsPatients with confirmed COVID-19 and ICU admission were enrolled in a retrospective, observational, cross-sectional study. The medians of C-reactive protein (CRP; ≥13.8 mg/dl) and the neutrophil-to-lymphocyte ratio (NLR; ≥12.6) upon admission were used to dichotomize patients.
resultsOf the 73 patients, 63% were men; the average age was 56 years, and the median length of hospital stay was 10 (25th: 4; 75th: 17) days. When nutrition risk screening tools were used, 85% were at risk according to Nutritional Risk Screening (≥3 points), whereas 42% had high risk according to the Modified Nutrition Risk in the Critically Ill (mNUTRIC; ≥5 points), and 57% were moderately or severely malnourished according to the Subjective Global Assessment (B or C). Mortality was higher in the group with NLR ≥12.6 than in the group with NLR <12.6, with no difference between CRP groups. A significant association was found only between NLR and mNUTRIC, even when adjusted by sex, age, and body mass index (odds ratio, 1.36; 95% CI, 1.06-1.76; P = 0.016), but not between CRP and nutrition risk.
conclusionAlthough the inflammatory marker CRP is the most used in hospital clinical practice, we found that only NLR was associated with nutrition risk (NUTRIC score).
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