Evidence map›Paper›PMID 34961951›Full record

ArticleAmerican journal of industrial medicine2022

Case-fatality study of workers and residents with radiographic asbestos disease in Libby, Montana.

Albert Miller, Charles B Black, Gregory Loewen, Curtis W Noonan, Tracy McNew, Alan C Whitehouse, Arthur L Frank

Open access · hybridAbstract read
In one paragraph

Article in American journal of industrial medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Albert MillerIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Charles B BlackCenter for Asbestos Related Disease, Libby, Montana, USA.
Gregory LoewenWashington State University, Spokane, Washington, USA.ORCID 0000-0002-7185-0796
Curtis W NoonanUniversity of Montana, Missoula, Montana, USA.
Tracy McNewCenter for Asbestos Related Disease, Libby, Montana, USA.ORCID 0000-0002-4302-1114
Alan C WhitehouseDrexel University, Philadelphia, Pennsylvania, USA.
Arthur L FrankDepartment of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, Pennsylvania, USA.
Center for Asbestos Related Disease · USDrexel University · USIcahn School of Medicine at Mount Sinai · USUniversity of Montana · USWashington State University Spokane · US

Funding

Wildfires and Cardiovascular Health: Evaluating Associations and Intervention StrategiesP20GM130418 · NIGMS · UNIVERSITY OF MONTANA · PI Curtis William Noonan · 2020 to 2026
$17.9M
Libby Epidemiology Research ProgramR01TS000099 · TS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FLORES, RAJA M. · 2009 to 2013
$4.8M
ATSDR CDC HHS R01 TS000099NIGMS NIH HHS P20 GM130418
6 · The paper itself

Abstract

backgroundVermiculite ore from Libby, Montana contains on average 24% of a mixture of toxic and carcinogenic amphibole asbestiform fibers. These comprise primarily winchite (84%), with smaller quantities of richterite (11%) and tremolite (6%), which are together referred to as Libby amphibole (LA).

methodsA total of 1883 individuals who were occupationally and/or environmentally exposed to LA and were diagnosed with asbestos-related pleuropulmonary disease (ARPPD) following participation in communitywide screening programs supported by the Agency for Toxic Substances and Disease Registry (ATSDR) and followed up at the Center for Asbestos Related Disease (CARD) between 2000 and 2010. There were 203 deaths of patients with sufficient records and radiographs. Best clinical and radiologic evidence was used to determine the cause of death, which was compared with death certificates.

resultsAsbestos-related mortality was 55% (n = 112) in this series of 203 patients. Of the 203 deaths, 34 (17%) were from asbestos-related malignancy, 75 (37%) were from parenchymal asbestosis, often with pleural fibrosis, and 3 (1.5%) were from respiratory failure secondary to pleural thickening.

conclusionsAsbestos is the leading cause of mortality following both occupational and nonoccupational exposure to LA in those with asbestos-related disease.

Indexed as

AsbestosAsbestosisPleural DiseasesAsbestos, AmphiboleHumansMontanaAsbestosAsbestos, Amphiboleasbestos-related pleuropulmonary disease (ARPPD)case fatalitylamellar pleural thickening (LPT)Libby amphibole (LA)mortalityvermiculite

Identifiers

PMID34961951
PMCPMC9303583
OpenAlexW4200284058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.