Evidence map›Paper›PMID 34961501›Full record

ArticleBMC ophthalmology2021

Xen45 gel stent ab interno trimming for ostium occlusion: case report.

Filippo Tatti, Pietro Gentile, Lorenzo Mangoni, Giuseppe Demarinis, Pietro Napoli, Maurizio Fossarello

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Filippo TattiDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Pietro GentileDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Lorenzo MangoniDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Giuseppe DemarinisDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Pietro NapoliDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Maurizio FossarelloDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy. maurizio.fossarello@gmail.com.ORCID http://orcid.org/0000-0003-1520-7760
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the XEN gel stent low-risk profile, various complications following the implant have been described, including internal and external occlusion, with a consequent postoperative rise in intraocular pressure (IOP). In this case report we aimed to present a XEN45 stent internal occlusion successfully treated by trimming in situ its proximal end with a 25 G vitreous scissors using a bimanual technique. CASE PRESENTATION: A 63-year-old male patient affected by primary open angle glaucoma (IOP = 25 mmHg) and a full thickness macular hole in his right eye, underwent ab-interno Xen gel stent implantation and, 1 month later, a 25 G vitrectomy surgery. Despite a significant IOP reduction after stent implant, 6 days after vitrectomy, IOP increased (25 mmHg) and the conjunctival bleb flattened following occlusion of stent internal ostium by a clot of presumed fibrinous material. The Nd:YAG laser failed to remove the clot, so that we decided to snip a small bit of the proximal end of the Xen tube (about 0,5 mm length) with a 25 G vitreous scissors, using a bimanual technique. In the postoperative day 1 and month 1, the IOP was 8 mmHg and 12 mmHg, respectively. The Anterior Segment OCT confirmed a functional, layered, filtering bleb, and the normal appearance and patency of the XEN proximal segment. No side effects from the intervention were observed.

conclusionsAb interno trimming with vitreous scissors of the occluded proximal end of the XEN stent may represent a safe, rapid and efficient method to restore aqueous humor subconjunctival drainage.

Indexed as

Glaucoma Drainage ImplantsGlaucoma, Open-AngleHumansIntraocular PressureMaleMiddle AgedStentsTonometry, OcularTreatment OutcomeCase reportComplicationsGlaucomaMIGSXEN

Identifiers

PMID34961501
PMCPMC8711208
OpenAlexW4200389237

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.