Evidence map›Paper›PMID 34961157›Full record

ArticlePlants (Basel, Switzerland)2021

Alkaloid Profiling and Cholinesterase Inhibitory Potential of

Luciana R Tallini, Angelo Carrasco, Karen Acosta León, Diego Vinueza, Jaume Bastida, Nora H Oleas

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Chemical Survey of Three Species of the GenusPlants (Basel, Switzerland) · 2022
    Article
  4. The Phytochemistry and Pharmacology ofMolecules (Basel, Switzerland) · 2022
    Review
  5. StandardizedIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Luciana R TalliniPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre 90610-000, Brazil.
Angelo CarrascoGrupo de Investigación de Productos Naturales y Farmacia, Facultad de Ciencias, Escuela Superior Politécnica del Chimborazo, Panamericana Sur km 1 1/2, Riobamba EC060155, Ecuador.ORCID 0000-0001-9717-299X
Karen Acosta LeónGrupo de Investigación de Productos Naturales y Farmacia, Facultad de Ciencias, Escuela Superior Politécnica del Chimborazo, Panamericana Sur km 1 1/2, Riobamba EC060155, Ecuador.
Diego VinuezaGrupo de Investigación de Productos Naturales y Farmacia, Facultad de Ciencias, Escuela Superior Politécnica del Chimborazo, Panamericana Sur km 1 1/2, Riobamba EC060155, Ecuador.
Jaume BastidaGrup de Productes Naturals, Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII, #27-31, 08028 Barcelona, Spain.
Nora H OleasCentro de Investigación de la Biodiversidad y Cambio Climático (BioCamb) e Ingeniería en Biodiversidad y Recursos Genéticos, Facultad de Ciencias de Medio Ambiente, Universidad Tecnológica Indoamérica, Machala y Sabanilla, Quito EC170301, Ecuador.
Escuela Superior Politécnica del Chimborazo · ECUniversidade Federal do Rio Grande do Sul · BRUniversidad Indoamérica · ECUniversitat de Barcelona · ES

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Processo 13553135National Institute of Science and Technology - INCT BioNat 465637/2014-0Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo 416RT0511Universidad Tecnológica Indoamérica 02-BioCamb-(20162020).
6 · The paper itself

Abstract

Natural products are one of the main sources for developing new drugs. The alkaloids obtained from the plant family Amaryllidaceae have interesting structures and biological activities, such as acetylcholinesterase inhibition potential, which is one of the mechanisms used for the palliative treatment of Alzheimer's disease symptoms. Herein we report the alkaloidal profile of bulbs and leaves extracts of

Indexed as

AChEAmaryllidaceae alkaloidsBuChECrinum × amabileGC-MS

Identifiers

PMID34961157
PMCPMC8707120
OpenAlexW4200565981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.