ArticlePolymers2021
The Effects of Curcumin Nanoparticles Incorporated into Collagen-Alginate Scaffold on Wound Healing of Skin Tissue in Trauma Patients.
Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 49 citations in OpenAlex.
- Curcumin-based biocompatible nanocarriers: a contemporary perspective in functional foods and biomedical applications.Discover nano · 2025Review
- Hierarchical Delivery of Anti-Inflammatory Compound and Stem Cells for Chronic Wounds.Pharmaceutics · 2025Article
- Curcumin-Loaded Drug Delivery Systems for Acute and Chronic Wound Management: A Review.Bioengineering (Basel, Switzerland) · 2025Review
- Limonene encapsulated alginate/collagen as antibiofilm drug against Acinetobacter baumannii.BMC biotechnology · 2024Article
- Evolution of Hybrid Hydrogels: Next-Generation Biomaterials for Drug Delivery and Tissue Engineering.Gels (Basel, Switzerland) · 2024Review
- Review
- The Fabrication of Polymer-Based Curcumin-Loaded Formulation as a Drug Delivery System: An Updated Review from 2017 to the Present.Pharmaceutics · 2024Review
- Curcumin-infused nanostructured lipid carriers: a promising strategy for enhancing skin regeneration and combating microbial infection.BMC veterinary research · 2023Article
- Natural and Synthetic Polymeric Biomaterials for Application in Wound Management.Journal of functional biomaterials · 2023Review
- Transforming Wound Management: Nanomaterials and Their Clinical Impact.Pharmaceutics · 2023Review
- Article
- Polymeric biomaterials for wound healing.Frontiers in bioengineering and biotechnology · 2023Review
- Article
- Different Curcumin-Loaded Delivery Systems for Wound Healing Applications: A Comprehensive Review.Pharmaceutics · 2022Review
- Wound-Healing Effects of Curcumin and Its Nanoformulations: A Comprehensive Review.Pharmaceutics · 2022Review
- Alginate as a Promising Biopolymer in Drug Delivery and Wound Healing: A Review of the State-of-the-Art.International journal of molecular sciences · 2022Review
- Mesenchymal Stem Cell-Derived Extracellular Vesicles as Non-Coding RNA Therapeutic Vehicles in Autoimmune Diseases.Pharmaceutics · 2022Review
- SuperiorFrontiers in microbiology · 2022Article
- Investigations on the Influence of Collagen Type on Physicochemical Properties of PVP/PVA Composites Enriched with Hydroxyapatite Developed for Biomedical Applications.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing is a biological process that is mainly crucial for the rehabilitation of injured tissue. The incorporation of curcumin (Cur) into a hydrogel system is used to treat skin wounds in different diseases due to its hydrophobic character. In this study, sodium alginate and collagen, which possess hydrophilic, low toxic, and biocompatible properties, were utilized. Collagen/alginate scaffolds were synthesized, and nanocurcumin was incorporated inside them; their interaction was evaluated by FTIR spectroscopy. Morphological studies investigated structures of the samples studied by FE-SEM. The release profile of curcumin was detected, and the cytotoxic test was determined on the L929 cell line using an MTT assay. Analysis of tissue wound healing was performed by H&E staining. Nanocurcumin was spherical, its average particle size was 45 nm, and the structure of COL/ALG scaffold was visible. The cell viability of samples was recorded in cells after 24 h incubation. Results of in vivo wound healing remarkably showed CUR-COL/ALG scaffold at about 90% (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.