Evidence map›Paper›PMID 34960784›Full record

ReviewViruses2021

Inositol Phosphates and Retroviral Assembly: A Cellular Perspective.

Clifton L Ricaña, Robert A Dick

Abstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clifton L RicañaDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-9733-9136
Robert A DickDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

Funding

Retrovirus Structure and Assembly with Inositol PhosphatesR01AI147890 · NIAID · EMORY UNIVERSITY · PI DICK, ROBERT A · 2019 to 2022
$1.6M
Structure and Assembly of RetrovirusesR01AI150454 · NIAID · CORNELL UNIVERSITY · PI VOGT, VOLKER M. · 2019 to 2020
$719k
National Institute of Allergy and Infectious Diseases RO1AI147890National Institute of Allergy and Infectious Diseases RO1AI150454NIAID NIH HHS R01 AI147890
6 · The paper itself

Abstract

Understanding the molecular mechanisms of retroviral assembly has been a decades-long endeavor. With the recent discovery of inositol hexakisphosphate (IP6) acting as an assembly co-factor for human immunodeficiency virus (HIV), great strides have been made in retroviral research. In this review, the enzymatic pathways to synthesize and metabolize inositol phosphates (IPs) relevant to retroviral assembly are discussed. The functions of these enzymes and IPs are outlined in the context of the cellular biology important for retroviruses. Lastly, the recent advances in understanding the role of IPs in retroviral biology are surveyed.

Indexed as

Biosynthetic Pathwaysgag Gene Products, Human Immunodeficiency VirusHIV InfectionsHumansInositol PhosphatesPhytic AcidRetroviridaeVirionVirus Assemblygag Gene Products, Human Immunodeficiency VirusInositol PhosphatesPhytic AcidHIVinositol hexakisphosphateinositol phosphate metabolismInsP5InsP6IP5IP6lentivirusreview

Identifiers

PMID34960784
PMCPMC8703376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.