Evidence map›Paper›PMID 34960774›Full record

ArticleViruses2021

Knock-Out of Retrovirus Receptor Gene

Anna Koslová, Pavel Trefil, Jitka Mucksová, Veronika Krchlíková, Jiří Plachý, Jakub Krijt, Markéta Reinišová, Dana Kučerová, Josef Geryk, Jiří Kalina and 4 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Selection for Resilience in Livestock Production Systems.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Comparison of Multiple Strategies for Precision Transgene Knock-In inInternational journal of molecular sciences · 2023
    Article
  9. Avian Leukosis: Will We Be Able to Get Rid of It?Animals : an open access journal from MDPI · 2023
    Review
  10. Advances on genetic and genomic studies of ALV resistance.Journal of animal science and biotechnology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Anna KoslováInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.ORCID 0000-0002-6538-8005
Pavel TrefilBIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, Pohoří-Chotouň 90, 254 49 Jílové u Prahy, Czech Republic.
Jitka MucksováBIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, Pohoří-Chotouň 90, 254 49 Jílové u Prahy, Czech Republic.
Veronika KrchlíkováInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Jiří PlachýInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Jakub KrijtDepartment of Pediatrics and Inherited Metabolic Disorders, Charles University, First Faculty of Medicine and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Markéta ReinišováInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Dana KučerováInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Josef GerykInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Jiří KalinaBIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, Pohoří-Chotouň 90, 254 49 Jílové u Prahy, Czech Republic.ORCID 0000-0001-8057-7229
Filip ŠeniglInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Daniel EllederInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.ORCID 0000-0001-9041-5274
Viktor KožichDepartment of Pediatrics and Inherited Metabolic Disorders, Charles University, First Faculty of Medicine and General University Hospital in Prague, 128 08 Prague, Czech Republic.ORCID 0000-0001-5820-5277
Jiří HejnarInstitute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Czech Academy of Sciences · CZBIOPHARM (Czechia) · CZCharles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chicken Tva cell surface protein, a member of the low-density lipoprotein receptor family, has been identified as an entry receptor for avian leukosis virus of classic subgroup A and newly emerging subgroup K. Because both viruses represent an important concern for the poultry industry, we introduced a frame-shifting deletion into the chicken

Indexed as

AnimalsAvian Leukosis VirusAvian ProteinsChick EmbryoChickensFemaleFrameshift MutationGene EditingGene Knockout TechniquesMaleMethylmalonic AcidReceptors, VirusVitamin B 12Avian ProteinsMethylmalonic AcidReceptors, VirusTva receptorVitamin B 12avian leukosis virus subgroups A/Kgene editing in chickentvavitamin B12/cobalamin

Identifiers

PMID34960774
PMCPMC8708277
OpenAlexW4200346895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.