Evidence map›Paper›PMID 34960771›Full record

ArticleViruses2021

Idiopathic Chronic Diarrhea in Rhesus Macaques Is Not Associated with Enteric Viral Infections.

Eric Delwart, Michael J Tisza, Eda Altan, Yanpeng Li, Xutao Deng, Dennis J Hartigan-O'Connor, Amir Ardeshir

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. A review of chronic enterocolitis of rhesus macaques (Frontiers in veterinary science · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Eric DelwartVitalant Research Institute, 270 Masonic Ave, San Francisco, CA 94118, USA.ORCID 0000-0002-6296-4484
Michael J TiszaLaboratory of Cellular Oncology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.ORCID 0000-0003-1168-1617
Eda AltanVitalant Research Institute, 270 Masonic Ave, San Francisco, CA 94118, USA.ORCID 0000-0001-7903-6986
Yanpeng LiVitalant Research Institute, 270 Masonic Ave, San Francisco, CA 94118, USA.ORCID 0000-0002-0643-4809
Xutao DengVitalant Research Institute, 270 Masonic Ave, San Francisco, CA 94118, USA.
Dennis J Hartigan-O'ConnorCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.
Amir ArdeshirCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.ORCID 0000-0002-4330-4659
University of California, San Francisco · USNational Cancer Institute · USUniversity of California, Davis · USUniversity of California Davis Medical Center · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Viral etiology of idiopathic chronic diarrhea in rhesus macaquesR01AI123376 · NIAID · VITALANT · PI DELWART, ERIC L · 2016 to 2019
$2.0M
National Institute of Allergy and Infectious Diseases 5R01AI123376
6 · The paper itself

Abstract

While recent changes in treatment have reduced the lethality of idiopathic chronic diarrhea (ICD), this condition remains one of the most common causes of rhesus macaque deaths in non-human primate research centers. We compared the viromes in fecal swabs from 52 animals with late stage ICD and 41 healthy animals. Viral metagenomics targeting virus-like particles was used to identify viruses fecally shed by each animal. Five viruses belonging to the

Indexed as

AnimalsCase-Control StudiesChronic DiseaseDiarrheaFecesMacaca mulattaMetagenomicsVirus DiseasesCenote-Taker 2disease associationidiopathic chronic diarrheaviral metagenomicsvirome

Identifiers

PMID34960771
PMCPMC8707486
OpenAlexW4226247648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.