Evidence map›Paper›PMID 34960766›Full record

ArticleViruses2021

Spontaneous Mutation in the Movement Protein of Citrus Leprosis Virus C2, in a Heterologous Virus Infection Context, Increases Cell-to-Cell Transport and Generates Fitness Advantage.

Mikhail Oliveira Leastro, David Villar-Álvarez, Juliana Freitas-Astúa, Elliot Watanabe Kitajima, Vicente Pallás, Jesús Ángel Sánchez-Navarro

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mikhail Oliveira LeastroUnidade Laboratorial de Referência em Biologia Molecular Aplicada, Instituto Biológico, São Paulo 04014-900, Brazil.ORCID 0000-0003-3203-366X
David Villar-ÁlvarezInstituto de Biología Molecular y Celular de Plantas, Universidad Politécnica de Valencia-Consejo Superior de Investigaciones Científicas (CSIC), 46022 Valencia, Spain.
Juliana Freitas-AstúaUnidade Laboratorial de Referência em Biologia Molecular Aplicada, Instituto Biológico, São Paulo 04014-900, Brazil.ORCID 0000-0002-0506-6880
Elliot Watanabe KitajimaDepartamento de Fitopatologia e Nematologia, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo, Piracicaba 13418-900, Brazil.
Vicente PallásInstituto de Biología Molecular y Celular de Plantas, Universidad Politécnica de Valencia-Consejo Superior de Investigaciones Científicas (CSIC), 46022 Valencia, Spain.ORCID 0000-0003-4954-989X
Jesús Ángel Sánchez-NavarroInstituto de Biología Molecular y Celular de Plantas, Universidad Politécnica de Valencia-Consejo Superior de Investigaciones Científicas (CSIC), 46022 Valencia, Spain.ORCID 0000-0002-3320-2827
Consejo Superior de Investigaciones Científicas · ESInstituto Biológico · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous results using a movement defective alfalfa mosaic virus (AMV) vector revealed that citrus leprosis virus C (CiLV-C) movement protein (MP) generates a more efficient local movement, but not more systemic transport, than citrus leprosis virus C2 (CiLV-C2) MP, MPs belonging to two important viruses for the citrus industry. Here, competition experiment assays in transgenic tobacco plants (P12) between transcripts of AMV constructs expressing the cilevirus MPs, followed by several biological passages, showed the prevalence of the AMV construct carrying the CiLV-C2 MP. The analysis of AMV RNA 3 progeny recovered from P12 plant at the second viral passage revealed the presence of a mix of progeny encompassing the CiLV-C2 MP wild type (MP

Indexed as

MutationAlfalfa mosaic virusCitrusMovementPlants, Genetically ModifiedPlant Viral Movement ProteinsPlant VirusesVirus ReplicationPlant Viral Movement Proteinsalfalfa mosaic virus systemamino acid mutationcilevirusmovement proteinviral fitness

Identifiers

PMID34960766
PMCPMC8708801
OpenAlexW4200104583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.