Evidence map›Paper›PMID 34960753›Full record

ArticleViruses2021

A Novel Terrestrial Rabies Virus Lineage Occurring in South America: Origin, Diversification, and Evidence of Contact between Wild and Domestic Cycles.

Diego A Caraballo, Cristina Lema, Laura Novaro, Federico Gury-Dohmen, Susana Russo, Fernando J Beltrán, Gustavo Palacios, Daniel M Cisterna

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diego A CaraballoInstituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA), CONICET-Universidad de Buenos Aires, Ciudad Universitaria-Pabellón II, Buenos Aires C1428EHA, Argentina.ORCID 0000-0002-0345-7861
Cristina LemaServicio de Neurovirosis, Administración Nacional de Laboratorios e Institutos de Salud (ANLIS), Instituto Nacional de Enfermedades Infecciosas, "Dr. Carlos G. Malbrán", Av. Vélez Sarsfield 563, Buenos Aires C1282AFF, Argentina.
Laura NovaroDILAB, SENASA, Av. Paseo Colón 367, Buenos Aires C1063ACD, Argentina.
Federico Gury-DohmenInstituto de Zoonosis "Dr. Luis Pasteur", Av. Díaz Vélez 4821, Buenos Aires C1405DCD, Argentina.
Susana RussoDILAB, SENASA, Av. Paseo Colón 367, Buenos Aires C1063ACD, Argentina.
Fernando J BeltránInstituto de Zoonosis "Dr. Luis Pasteur", Av. Díaz Vélez 4821, Buenos Aires C1405DCD, Argentina.ORCID 0000-0001-9174-2672
Gustavo PalaciosDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-5062-1938
Daniel M CisternaServicio de Neurovirosis, Administración Nacional de Laboratorios e Institutos de Salud (ANLIS), Instituto Nacional de Enfermedades Infecciosas, "Dr. Carlos G. Malbrán", Av. Vélez Sarsfield 563, Buenos Aires C1282AFF, Argentina.ORCID 0000-0001-7614-9272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rabies virus (RABV) is characterized by a history dominated by host shifts within and among bats and carnivores. One of the main outcomes of long-term RABV maintenance in dogs was the establishment of variants in a wide variety of mesocarnivores. In this study, we present the most comprehensive phylogenetic and phylogeographic analysis, contributing to a better understanding of the origins, diversification, and the role of different host species in the evolution and diffusion of a dog-related variant endemic of South America. A total of 237 complete Nucleoprotein gene sequences were studied, corresponding to wild and domestic species, performing selection analyses, ancestral states reconstructions, and recombination analyses. This variant originated in Brazil and disseminated through Argentina and Paraguay, where a previously unknown lineage was found. A single host shift was identified in the phylogeny, from dog to the crab-eating fox (

Indexed as

AnimalsAnimals, DomesticAnimals, WildDog DiseasesDogsEvolution, MolecularFoxesNucleoproteinsPhylogenyRabiesRabies virusRecombination, GeneticSouth AmericaNucleoproteinsdog-relatedhost shiftnucleoproteinphylogenyrabiesrecombinationselection

Identifiers

PMID34960753
PMCPMC8707302

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.