Evidence map›Paper›PMID 34960713›Full record

ArticleViruses2021

Fc-Mediated E2-Dimer Subunit Vaccines of Atypical Porcine Pestivirus Induce Efficient Humoral and Cellular Immune Responses in Piglets.

Xujiao Ren, Ping Qian, Shudan Liu, Huanchun Chen, Xiangmin Li

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xujiao RenState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Ping QianState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Shudan LiuState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Huanchun ChenState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Xiangmin LiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Huazhong Agricultural University · CNCenter of Hubei Cooperative Innovation for Emissions Trading System · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital tremor (CT) type A-II in piglets is caused by an emerging atypical porcine pestivirus (APPV), which is prevalent in swine herds and a serious threat to the pig production industry. This study aimed to construct APPV E2 subunit vaccines fused with Fc fragments and evaluate their immunogenicity in piglets. Here, APPV E2Fc and E2ΔFc fusion proteins expressed in

Indexed as

Immunity, CellularImmunity, HumoralAnimalsAntibodies, ViralCell LineImmunogenicity, VaccineImmunoglobulin Fc FragmentsLymphocyte ActivationPestivirusPestivirus InfectionsProtein MultimerizationReceptors, IgGRecombinant Fusion ProteinsSwineSwine DiseasesTh2 CellsAntibodies, ViralImmunoglobulin Fc FragmentsReceptors, IgGRecombinant Fusion ProteinsVaccines, SubunitViral Structural ProteinsViral VaccinesAPPVcongenital tremordimerFc fragmentsubunit vaccine

Identifiers

PMID34960713
PMCPMC8703287
OpenAlexW4200164865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.