Evidence map›Paper›PMID 34960685›Full record

ArticleViruses2021

The Membrane-Anchoring Region of the AcMNPV P74 Protein Is Expendable or Interchangeable with Homologs from Other Species.

María Victoria Nugnes, Alexandra Marisa Targovnik, Adrià Mengual-Martí, María Victoria Miranda, Carolina Susana Cerrudo, Salvador Herrero, Mariano Nicolás Belaich

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

María Victoria NugnesLaboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Insectos, Instituto de Microbiología Básica y Aplicada, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, Bernal, Buenos Aires B1876BXD, Argentina.ORCID 0000-0001-8399-7907
Alexandra Marisa TargovnikCátedra de Biotecnología, Departamento de Microbiología, Inmunología, Biotecnología y Genética, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, Sexto Piso, Buenos Aires C1113AAD, Argentina.ORCID 0000-0003-4480-031X
Adrià Mengual-MartíDepartment of Genetics and University Institute of Biotechnology and Biomedicine-BIOTECMED, Universitat de València, Dr. Moliner 50, Valencia, 46100 Burjassot, Spain.ORCID 0000-0002-5458-3454
María Victoria MirandaCátedra de Biotecnología, Departamento de Microbiología, Inmunología, Biotecnología y Genética, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, Sexto Piso, Buenos Aires C1113AAD, Argentina.
Carolina Susana CerrudoLaboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Insectos, Instituto de Microbiología Básica y Aplicada, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, Bernal, Buenos Aires B1876BXD, Argentina.ORCID 0000-0003-1748-5385
Salvador HerreroDepartment of Genetics and University Institute of Biotechnology and Biomedicine-BIOTECMED, Universitat de València, Dr. Moliner 50, Valencia, 46100 Burjassot, Spain.ORCID 0000-0001-5690-2108
Mariano Nicolás BelaichLaboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Insectos, Instituto de Microbiología Básica y Aplicada, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, Bernal, Buenos Aires B1876BXD, Argentina.ORCID 0000-0002-3346-4587
National University of Quilmes · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baculoviruses are insect pathogens that are characterized by assembling the viral dsDNA into two different enveloped virions during an infective cycle: occluded virions (ODVs; immersed in a protein matrix known as occlusion body) and budded virions (BVs). ODVs are responsible for the primary infection in midgut cells of susceptible larvae thanks to the per os infectivity factor (PIF) complex, composed of at least nine essential viral proteins. Among them, P74 is a crucial factor whose activity has been identified as virus-specific. In this work, the

Indexed as

Amino Acid MotifsAnimalsCRISPR-Cas SystemsGenetic Complementation TestLarvaMothsNucleopolyhedrovirusesPhylogenyProtein DomainsRecombinant Fusion ProteinsSf9 CellsSpodopteraViral Envelope ProteinsAc-p74 protein, Autographa californica nucleopolyhedrovirusRecombinant Fusion ProteinsViral Envelope ProteinsAcMNPVbaculovirusCRISPR/Cas9HearSNPVP74Rachiplusia nuSeMNPVSpodoptera exigua

Identifiers

PMID34960685
PMCPMC8704774
OpenAlexW3215069640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.