Evidence map›Paper›PMID 34960679›Full record

ReviewViruses2021

Tribute to John C. Martin at the Twentieth Anniversary of the Breakthrough of Tenofovir in the Treatment of HIV Infections.

Erik De Clercq

Abstract readBiographyHistorical ArticleReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Erik De ClercqDepartment of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-2985-8890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At Bristol-Myers (BM) (1985-1990), John C. Martin started his HIV career with directing the clinical development of didanosine (ddI) and stavudine (d4T). During this period, he became aware of the acyclic nucleoside phosphonates (ANPs), such as (

Indexed as

AlanineAnti-HIV AgentsDrug Therapy, CombinationEmtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationHepatitis BHistory, 20th CenturyHistory, 21st CenturyHIVHIV InfectionsHumansPre-Exposure ProphylaxisReverse Transcriptase InhibitorsTenofovirAlanineAnti-HIV AgentsEmtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationReverse Transcriptase InhibitorsTenofovirtenofovir alafenamideCMVHIVTAFTDFtenofovir

Identifiers

PMID34960679
PMCPMC8705530

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.