Evidence map›Paper›PMID 34960670›Full record

ArticleViruses2021

COVID-19 In-Hospital Mortality in People with Diabetes Is Driven by Comorbidities and Age-Propensity Score-Matched Analysis of Austrian National Public Health Institute Data.

Faisal Aziz, Felix Aberer, Alexander Bräuer, Christian Ciardi, Martin Clodi, Peter Fasching, Mario Karolyi, Alexandra Kautzky-Willer, Carmen Klammer, Oliver Malle and 22 more

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Faisal AzizInterdisciplinary Metabolic Medicine Trials Unit, Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-0109-2969
Felix AbererInterdisciplinary Metabolic Medicine Trials Unit, Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-9947-1413
Alexander BräuerMedical Division of Endocrinology, Rheumatology and Acute Geriatrics, Hospital Ottakring, 1160 Vienna, Austria.
Christian CiardiClinical Division for Internal Medicine, Endocrinology, Diabetology and Metabolic Diseases, St. Vinzenz Hospital Zams, 6511 Zams, Austria.
Martin ClodiClinical Division for Internal Medicine, Konvent Hospital Barmherzige Brüder Linz, 4020 Linz, Austria.
Peter FaschingMedical Division of Endocrinology, Rheumatology and Acute Geriatrics, Hospital Ottakring, 1160 Vienna, Austria.
Mario Karolyi4th Medical Division with Infectiology, SMZ Süd-KFJ-Hospital Vienna, 1100 Vienna, Austria.
Alexandra Kautzky-WillerDivision for Endocrinology and Metabolism, Medical University of Vienna, AKH, 1090 Vienna, Austria.ORCID 0000-0002-3520-4105
Carmen KlammerClinical Division for Internal Medicine, Konvent Hospital Barmherzige Brüder Linz, 4020 Linz, Austria.
Oliver MalleInterdisciplinary Metabolic Medicine Trials Unit, Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.
Erich Pawelka4th Medical Division with Infectiology, SMZ Süd-KFJ-Hospital Vienna, 1100 Vienna, Austria.
Thomas PieberDivision of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0003-3554-0405
Slobodan PericDepartment of Medicine III and Karl Landsteiner, Institute for Metabolic Diseases and Nephrology, Clinic Hietzing, Vienna Health Care Group, 1130 Vienna, Austria.
Claudia RessDepartment for Internal Medicine I, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Michael SchranzDepartment for Inner Medicine, Paracelsus-Private Medical University, 5020 Salzburg, Austria.
Caren SourijDivision of Cardiology, Medical University of Graz, 8036 Graz, Austria.
Lars StechemesserDepartment for Inner Medicine, Paracelsus-Private Medical University, 5020 Salzburg, Austria.
Harald StinglClinical Division for Internal Medicine, Hospital Melk, 3390 Melk, Austria.
Hannah StöcherInterdisciplinary Metabolic Medicine Trials Unit, Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.
Thomas StulnigDepartment of Medicine III and Karl Landsteiner, Institute for Metabolic Diseases and Nephrology, Clinic Hietzing, Vienna Health Care Group, 1130 Vienna, Austria.
Norbert TripoltInterdisciplinary Metabolic Medicine Trials Unit, Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.
Michael WagnerClinical Division for Internal Medicine, Hospital Melk, 3390 Melk, Austria.
Peter WolfDivision for Endocrinology and Metabolism, Medical University of Vienna, AKH, 1090 Vienna, Austria.
Andreas ZitterlDepartment of Medicine III and Karl Landsteiner, Institute for Metabolic Diseases and Nephrology, Clinic Hietzing, Vienna Health Care Group, 1130 Vienna, Austria.
Alexander Christian ReisingerIntensive Care Unit, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-5773-5695
Jolanta Siller-MatulaDivision of Cardiology, Medical University of Vienna, AKH, 1090 Vienna, Austria.ORCID 0000-0001-6041-1635
Michael HummerAustrian National Public Health Institute, 1010 Vienna, Austria.
Othmar MoserDepartment of Exercise Physiology & Metabolism, Institute of Sports Science, University of Bayreuth, 95445 Bayreuth, Germany.
Dirk von-LewinskiDivision of Cardiology, Medical University of Graz, 8036 Graz, Austria.
Philipp EllerIntensive Care Unit, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0001-5537-3646
Susanne KaserDepartment for Internal Medicine I, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Harald SourijInterdisciplinary Metabolic Medicine Trials Unit, Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0003-3510-9594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is a matter of debate whether diabetes alone or its associated comorbidities are responsible for severe COVID-19 outcomes. This study assessed the impact of diabetes on intensive care unit (ICU) admission and in-hospital mortality in hospitalized COVID-19 patients.

methodsA retrospective analysis was performed on a countrywide cohort of 40,632 COVID-19 patients hospitalized between March 2020 and March 2021. Data were provided by the Austrian data platform. The association of diabetes with outcomes was assessed using unmatched and propensity-score matched (PSM) logistic regression.

results12.2% of patients had diabetes, 14.5% were admitted to the ICU, and 16.2% died in the hospital. Unmatched logistic regression analysis showed a significant association of diabetes (odds ratio [OR]: 1.24, 95% confidence interval [CI]: 1.15-1.34,

conclusionsPeople with diabetes were more likely to be admitted to ICU compared to those without diabetes. However, advanced age and comorbidities rather than diabetes itself were associated with increased in-hospital mortality in COVID-19 patients.

Indexed as

ComorbidityHospital MortalityPublic HealthAdultAgedAged, 80 and overAustriaCohort StudiesCOVID-19Diabetes MellitusFemaleHospitalizationHumansIntensive Care UnitsMaleMiddle AgedCOVID-19diabetesintensive caremortalitySARS-CoV-2

Identifiers

PMID34960670
PMCPMC8705658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.