Evidence map›Paper›PMID 34960656›Full record

ReviewViruses2021

Drugs of Abuse and Their Impact on Viral Pathogenesis.

Jason T Blackard, Kenneth E Sherman

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jason T BlackardDivision of Digestive Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0595, USA.ORCID 0000-0003-2876-3811
Kenneth E ShermanDivision of Digestive Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0595, USA.
University of Cincinnati Medical Center · US

Funding

Omics analysis of HIV during synthetic opioid exposureR61DA048439 · NIDA · UNIVERSITY OF CINCINNATI · PI BLACKARD, JASON T · 2019 to 2021
$2.1M
Omics analysis of HIV during synthetic opioid exposureR33DA048439 · NIDA · UNIVERSITY OF CINCINNATI · PI BLACKARD, JASON T · 2022 to 2023
$1.2M
National Institute of Drug Abuse DA048439 to JTBNIDA NIH HHS R33 DA048439NIDA NIH HHS R61 DA048439
6 · The paper itself

Abstract

Commonly misused substances such as alcohol, cocaine, heroin, methamphetamine, and opioids suppress immune responses and may impact viral pathogenesis. In recent years, illicit use of opioids has fueled outbreaks of several viral pathogens, including the human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). This review focuses on the myriad of mechanisms by which drugs of abuse impact viral replication and disease progression. Virus-drug interactions can accelerate viral disease progression and lead to increased risk of virus transmission.

Indexed as

AnimalsHepatitisHepatitis VirusesHIVHIV InfectionsHumansIllicit DrugsSubstance-Related DisordersIllicit Drugsdrug usehepatitis B virushepatitis C virusHIVopioid

Identifiers

PMID34960656
PMCPMC8707190
OpenAlexW3216599489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.