ArticleViruses2021
West Nile Virus Vaccination Protects against Usutu Virus Disease in Mice.
Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 20 citations in OpenAlex.
- A yellow fever 17D and Usutu virus chimera with rationally designed mutations in the envelope protein is lethal in an IfnarVirology journal · 2026Article
- Susceptibility of wild and domestic songbirds to Usutu virus.PLoS neglected tropical diseases · 2026Article
- Article
- Extrapolation and comparison of West Nile virus- and Usutu virus-associated neurological diseases in humans: linking pathology to clinical symptoms.Clinical microbiology reviews · 2025Review
- Cross-protection against St. Louis encephalitis virus and Usutu virus by West Nile virus convalescent plasma.Virology · 2025Article
- Cross-Protection between West Nile Virus and Emerging Flaviviruses in Wild Birds.The American journal of tropical medicine and hygiene · 2025Article
- Dose and strain dependent lethality of Usutu virus in an IfnarNpj viruses · 2025Article
- Generating prophylactic immunity against arboviruses in vertebrates and invertebrates.Nature reviews. Immunology · 2024Review
- Herpesvirus and Subsequent Usutu Virus Infection in a Great Grey Owl (Animals : an open access journal from MDPI · 2024Article
- Review
- Development and evaluation of neutralizing antibodies for cross-protection against West Nile virus and Japanese encephalitis virus.Infectious medicine · 2023Article
- Epidemiology, surveillance and diagnosis of Usutu virus infection in the EU/EEA, 2012 to 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Review
- First Detection and Molecular Characterization of Usutu Virus inMicroorganisms · 2023Article
- Article
- Cross-reactive antibodies against Langat virus protect mice from lethal tick-borne encephalitis virus infection.Frontiers in immunology · 2023Article
- Usutu virus: An emerging flavivirus with potential threat to public health in Africa: Nigeria as a case study.Frontiers in veterinary science · 2023Review
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
West Nile virus (WNV) and Usutu virus (USUV) are mosquito-borne flaviviruses that can cause neuroinvasive disease in humans. WNV and USUV circulate in both Africa and Europe and are closely related. Due to antigenic similarity, WNV-specific antibodies and USUV-specific antibodies have the potential to bind heterologous viruses; however, it is unclear whether this interaction may offer protection against infection. To investigate how prior WNV exposure would influence USUV infection, we used an attenuated WNV vaccine that contains the surface proteins of WNV in the backbone of a dengue virus 2 vaccine strain and protects against WNV disease. We hypothesized that vaccination with this attenuated WNV vaccine would protect against USUV infection. Neutralizing responses against WNV and USUV were measured in vitro using sera following vaccination. Sera from vaccinated CD-1 and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.