ArticleSensors (Basel, Switzerland)2021
Diagnosis of Bone Mineral Density Based on Backscattering Resonance Phenomenon Using Coregistered Functional Laser Photoacoustic and Ultrasonic Probes.
Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Qualitative Classification of Proximal Femoral Bone Using Geometric Features and Texture Analysis in Collected MRI Images for Bone Density Evaluation.Sensors (Basel, Switzerland) · 2023Article
- Micro-/Nano-Fiber Sensors and Optical Integration Devices.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Dual-energy X-ray absorptiometry (DXA) machines based on bone mineral density (BMD) represent the gold standard for osteoporosis diagnosis and assessment of fracture risk, but bone strength and toughness are strongly correlated with bone collagen content (CC). Early detection of osteoporosis combined with BMD and CC will provide improved predictability for avoiding fracture risk. The backscattering resonance (BR) phenomenon is present in both ultrasound (US) and photoacoustic (PA) signal transmissions through bone, and the peak frequencies of BR can be changed with BM and CC. This phenomenon can be explained by the formation of standing waves within the pores. Simulations were then conducted for the same bone µCT images and the resulting resonance frequencies were found to match those predicted using the standing wave hypothesis. Experiments were performed on the same bone sample using an 808 nm wavelength laser as the PA source and 3.5 MHz ultrasonic transducer as the US source. The backscattering resonance effect was observed in the transmitted waves. These results verify our hypothesis that the backscattering resonance phenomenon is present in both US and PA signal transmissions and can be explained using the standing waves model, which will provide a suitable method for the early detection of osteoporosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.