Evidence map›Paper›PMID 34960047›Full record

ArticleNutrients2021

The Antidiabetic Effect of Grape Pomace Polysaccharide-Polyphenol Complexes.

Filipa Campos, Andreia F Peixoto, Pedro A R Fernandes, Manuel A Coimbra, Nuno Mateus, Victor de Freitas, Iva Fernandes, Ana Fernandes

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Filipa CamposREQUIMTE-Laboratório Associado Para a Química Verde, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
Andreia F PeixotoREQUIMTE-Laboratório Associado Para a Química Verde, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.ORCID 0000-0002-1176-9064
Pedro A R FernandesLAQV/REQUIMTE, REQUIMTE-Laboratório Associado Para a Química Verde, Departmento de Química, Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4647-5274
Manuel A CoimbraLAQV/REQUIMTE, REQUIMTE-Laboratório Associado Para a Química Verde, Departmento de Química, Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.ORCID 0000-0001-8898-6342
Nuno MateusREQUIMTE-Laboratório Associado Para a Química Verde, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.ORCID 0000-0002-9318-9732
Victor de FreitasREQUIMTE-Laboratório Associado Para a Química Verde, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
Iva FernandesREQUIMTE-Laboratório Associado Para a Química Verde, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.ORCID 0000-0003-2297-0086
Ana FernandesREQUIMTE-Laboratório Associado Para a Química Verde, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
Universidade do Porto · PTRede de Química e Tecnologia · PT

Funding

AgriFood XXI I&DT project, European Regional Development Fund (ERDF), through the NORTE2020 (Programa Operacional Regional do Norte 2014/2020) NORTE-01-0145-FEDER-000041
6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic metabolic diseases of the 21st century. Nevertheless, its prevalence might be attenuated by taking advantage of bioactive compounds commonly found in fruits and vegetables. This work is focused on the recovery of polyphenols and polysaccharide-polyphenol conjugates from grape pomace for T2DM management and prevention. Bioactives were extracted by solid-liquid extraction and by pressurized hot water extraction (PHWE). Polyphenolic fraction recovered by PHWE showed the highest value for total phenolic content (427 μg GAE.mg

Indexed as

alpha-Amylasesalpha-GlucosidasesCaco-2 CellsGlycoside Hydrolase InhibitorsHumansHypoglycemic AgentsPlant ExtractsPolyphenolsPolysaccharidesVitisalpha-Amylasesalpha-GlucosidasesGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant ExtractsPolyphenolsPolysaccharidesanthocyaninsdiabetes mellituspolyphenolspolysaccharide–polyphenol conjugatespolysaccharidespressurized hot water extraction

Identifiers

PMID34960047
PMCPMC8709276
OpenAlexW4200055456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.