ArticleNutrients2021
Association between Vitamin D and Dental Caries in a Sample of Canadian and American Preschool-Aged Children.
Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis.Oral health & preventive dentistry · 2024Pooled it
- The relationship between nutrition, diet, and early childhood caries: A cross-sectional study using 2009 to 2014 NHANES data.Medicine · 2026Article
- Oral Health Practices Among Indigenous Mothers and Young Children (0-36 Months) in Northwest Territories, Canada.International journal of dentistry · 2025Article
- Early childhood caries and their association with serum iron, serum ferritin, serum albumin, and Vitamin D.Journal of family medicine and primary care · 2025Article
- The Role of Serum Vitamin D Levels and Vitamin D Receptor (Children (Basel, Switzerland) · 2024Article
- A Systematic Review of the Relationship between Serum Vitamin D Levels and Caries in the Permanent Teeth of Children and Adolescents.Dentistry journal · 2024Review
- Combined effect of dietary calcium consumption and physical activity on dental caries in children and adolescents: a study of the NHANES database.BMC oral health · 2024Article
- Clinical Correlation of Vitamin D Deficiency and Early Childhood Caries: A Cross-Sectional Study in Western Rajasthan.Journal of pharmacy & bioallied sciences · 2024Article
- Dental caries in children and vitamin D deficiency: a narrative review.European journal of pediatrics · 2024Review
- The association between serum vitamin D status and dental caries or molar incisor hypomineralisation in 7-9-year-old Norwegian children: a cross-sectional study.BMC public health · 2024Article
- Relationship between vitamin D status and caries experience in a group of Egyptian children: a cross-sectional study.BMC oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInadequate vitamin D levels may increase the risk of caries during childhood. The purpose of this study was to investigate the association between 25-hydroxyvitamin D (25(OH)D) status and severe early childhood caries (S-ECC) in preschool children.
methodsData were obtained from children <72 months of age in two case-control studies in Winnipeg, Manitoba and Richmond, Virginia. Serum analysis assessed 25(OH)D, calcium and parathyroid concentrations. Data on demographics, dental history and oral hygiene were obtained via questionnaires. Bivariate and multiple logistic regression analyses were performed to assess the relationships between demographic and biological variables and S-ECC. A
resultsData were available for 200 children with S-ECC and 144 caries-free controls. Children with S-ECC had significantly lower 25(OH)D levels than those who were caries-free (
conclusionsThis study provides additional evidence of an association between nutritional status, specifically vitamin D and calcium levels, and S-ECC.
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Registered trials
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