Evidence map›Paper›PMID 34959912›Full record

SynthesisNutrients2021

Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review.

Juan Mielgo-Ayuso, Laura Pietrantonio, Aitor Viribay, Julio Calleja-González, Jerónimo González-Bernal, Diego Fernández-Lázaro

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Effects of L-carnitine on healing of Achilles tendon in rats.Joint diseases and related surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Juan Mielgo-AyusoDepartment of Health Sciences, Faculty of Health Sciences, University of Burgos, 09001 Burgos, Spain.ORCID 0000-0002-6554-4602
Laura PietrantonioFaculty of Sport Science, Universidad Europea de Madrid, 28670 Madrid, Spain.
Aitor ViribayGlut4Science, Physiology, Nutrition and Sport, 01004 Vitoria-Gasteiz, Spain.
Julio Calleja-GonzálezDepartment of Physical Education and Sport, Faculty of Education and Sport, University of the Basque Country, 01007 Vitoria, Spain.ORCID 0000-0003-2575-7168
Jerónimo González-BernalDepartment of Health Sciences, Faculty of Health Sciences, University of Burgos, 09001 Burgos, Spain.
Diego Fernández-LázaroDepartment of Cellular Biology, Histology and Pharmacology, Faculty of Health Sciences, Campus of Soria, University of Valladolid, 42003 Soria, Spain.ORCID 0000-0002-6522-8896
Universidad de Burgos · ESUniversidad de Valladolid · ESUniversidad Europea de Madrid · ESUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-Carnitine (l-C) and any of its forms (glycine-propionyl l-Carnitine (GPL-C) or l-Carnitine l-tartrate (l-CLT)) has been frequently recommended as a supplement to improve sports performance due to, among others, its role in fat metabolism and in maintaining the mitochondrial acetyl-CoA/CoA ratio. The main aim of the present systematic review was to determine the effects of oral l-C supplementation on moderate- (50-79% V˙O

Indexed as

Dietary SupplementsAdministration, OralAthletic PerformanceCarnitineExerciseFemaleHumansMaleSports Nutritional Physiological PhenomenaTime FactorsCarnitineaerobic performanceanaerobic performancelipid oxidationrecoverysports nutrition

Identifiers

PMID34959912
PMCPMC8704793
OpenAlexW4200330222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.