Evidence map›Paper›PMID 34959847›Full record

Trial reportNutrients2021

Modified Citrus Pectin Treatment in Non-Metastatic Biochemically Relapsed Prostate Cancer: Results of a Prospective Phase II Study.

Daniel Keizman, Moshe Frenkel, Avivit Peer, Igal Kushnir, Eli Rosenbaum, David Sarid, Ilan Leibovitch, Roy Mano, Ofer Yossepowitch, David Margel and 6 more

Registry-linked trialOpen access · goldAbstract readClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06661044 (Exploiting Human Microbiota-associated in Vivo Models for Mechanistic Studies to Understand the Benefits of Dietary Fibre Supplementation in Patients With Prostate Cancer), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06661044 completednot on this mapstarted 2024, after this paper: background citation

Exploiting Human Microbiota-associated in Vivo Models for Mechanistic Studies to Understand the Benefits of Dietary Fibre Supplementation in Patients With Prostate Cancer

TypeobservationalSponsorUniversity of AberdeenRan2024 to 2025Enrolled6ConditionsProstate Cancer (Adenocarcinoma)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Daniel KeizmanDepartment of Oncology, Tel-Aviv Sourasky Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Moshe FrenkelDepartment of Oncology, Rambam Medical Center, Haifa 3109601, Israel.
Avivit PeerDepartment of Oncology, Rambam Medical Center, Haifa 3109601, Israel.
Igal KushnirDepartment of Oncology, Meir Medical Center and Sackler School of Medicine, Tel-Aviv University, Kfar-Saba 4428164, Israel.
Eli RosenbaumDepartment of Oncology, Rabin Medical Center, Petah-Tikva 4941492, Israel.
David SaridDepartment of Oncology, Tel-Aviv Sourasky Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Ilan LeibovitchDepartment of Urology, Meir Medical Center, Kfar-Saba 4439246, Israel.
Roy ManoDepartment of Urology, Tel-Aviv Sourasky Medical Center, Tel-Aviv 69978, Israel.
Ofer YossepowitchDepartment of Urology, Tel-Aviv Sourasky Medical Center, Tel-Aviv 69978, Israel.
David MargelDepartment of Urology, Rabin Medical Center, Petah-Tikva 4941492, Israel.
Ido WolfDepartment of Oncology, Tel-Aviv Sourasky Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Ravit GevaDepartment of Oncology, Tel-Aviv Sourasky Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Hadas DreslerDepartment of Oncology, Shaare Zedek Medical Center, Jerusalem 9103102, Israel.
Keren RouvinovDepartment of Oncology, Soroka Medical Center, Beer-Sheva 8428760, Israel.
Noa RapoportDepartment of Oncology, Meir Medical Center and Sackler School of Medicine, Tel-Aviv University, Kfar-Saba 4428164, Israel.
Isaac EliazAmitabha Medical Clinic and Healing Center, Santa Rosa, CA 95401, USA.
Tel Aviv Sourasky Medical Center · ILRabin Medical Center · ILRambam Health Care Campus · ILTel Aviv University · ILMeir Medical Center · ILShaare Zedek Medical Center · ILSoroka Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal therapy of biochemically relapsed prostate cancer (BRPC) after local treatment is elusive. An established modified citrus pectin (PectaSol

Indexed as

AdenocarcinomaAgedAged, 80 and overDisease ProgressionHumansMaleMiddle AgedNeoplasm Recurrence, LocalPectinsProspective StudiesProstatic NeoplasmsTime FactorsTreatment Outcomecitrus pectinPectinsmodified citrus pectinnon-metastatic biochemically relapsed prostate cancerPectaSolPSA doubling time

Identifiers

PMID34959847
PMCPMC8706421
OpenAlexW3216344258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.