Evidence map›Paper›PMID 34959786›Full record

ArticleNutrients2021

Pea Proteins Have Anabolic Effects Comparable to Milk Proteins on Whole Body Protein Retention and Muscle Protein Metabolism in Old Rats.

Jérôme Salles, Christelle Guillet, Olivier Le Bacquer, Carmen Malnero-Fernandez, Christophe Giraudet, Véronique Patrac, Alexandre Berry, Philippe Denis, Corinne Pouyet, Marine Gueugneau and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jérôme SallesUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Christelle GuilletUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Olivier Le BacquerUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Carmen Malnero-FernandezCosucra-Groupe S.A., 7740 Warcoing, Belgium.
Christophe GiraudetUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Véronique PatracUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Alexandre BerryUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Philippe DenisUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Corinne PouyetUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Marine GueugneauUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0001-8871-7345
Yves BoirieUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-3999-1599
Heidi JacobsCosucra-Groupe S.A., 7740 Warcoing, Belgium.
Stéphane WalrandUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, INRAE, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Institut Pascal · FR

Funding

Cosucra 2021
6 · The paper itself

Abstract

Plant proteins are attracting rising interest due to their pro-health benefits and environmental sustainability. However, little is known about the nutritional value of pea proteins when consumed by older people. Herein, we evaluated the digestibility and nutritional efficiency of pea proteins compared to casein and whey proteins in old rats. Thirty 20-month-old male Wistar rats were assigned to an isoproteic and isocaloric diet containing either casein (CAS), soluble milk protein (WHEY) or Pisane™ pea protein isolate for 16 weeks. The three proteins had a similar effect on nitrogen balance, true digestibility and net protein utilization in old rats, which means that different protein sources did not alter body composition, tissue weight, skeletal muscle protein synthesis or degradation. Muscle mitochondrial activity, inflammation status and insulin resistance were similar between the three groups. In conclusion, old rats used pea protein with the same efficiency as casein or whey proteins, due to its high digestibility and amino acid composition. Using these plant-based proteins could help older people diversify their protein sources and more easily achieve nutritional intake recommendations.

Indexed as

Amino AcidsAnabolic AgentsAnimalsCaseinsDigestionMaleMilk ProteinsMuscle ProteinsMuscle, SkeletalNutritive ValuePea ProteinsProteolysisRatsRats, WistarWhey ProteinsAmino AcidsAnabolic AgentsCaseinsMilk ProteinsMuscle ProteinsPea ProteinsWhey Proteinsmuscle protein metabolismpea proteinsplant proteinsprotein digestibilitysarcopeniaskeletal muscle

Identifiers

PMID34959786
PMCPMC8704096
OpenAlexW3217782917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.