Evidence map›Paper›PMID 34959735›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

The Role of TRPA1 Channels in the Central Processing of Odours Contributing to the Behavioural Responses of Mice.

János Konkoly, Viktória Kormos, Balázs Gaszner, Zoltán Sándor, Angéla Kecskés, Ammar Alomari, Alíz Szilágyi, Beatrix Szilágyi, Dóra Zelena, Erika Pintér

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Correlation of TRPA1 RNAscope and Agonist Responses.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

János KonkolyDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Viktória KormosDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0002-3360-2425
Balázs GasznerCentre for Neuroscience, Szentágothai Research Centre of the University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0003-2830-2732
Zoltán SándorDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Angéla KecskésDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0003-3538-588X
Ammar AlomariDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Alíz SzilágyiInstitute of Physiology, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Beatrix SzilágyiInstitute of Physiology, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Dóra ZelenaCentre for Neuroscience, Szentágothai Research Centre of the University of Pécs, H-7624 Pécs, Hungary.
Erika PintérDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0001-9898-632X
University of Pecs · HUHUN-REN Institute of Experimental Medicine · HU

Funding

EFOP EFOP-3.6.2.-16-2017-00008FIKP (the Thematic Excellence Program 2020 - Institutional Excellence Sub-programme / Nation-al Excellence Sub-program of the Ministry for Innovation and Technology in Hungary, within the framework of the 5. thematic programme of the Pécs of University) 2020-4.1.1-TKP2020Hungarian Scientific Research Fund NKFIH, FK124188KTIA Hungarian Brain Research Program 2.0 2017-1.2.1.-NKP-2017-00002National Research, Development and Innovation K120311, K131406, K138763National Research, Development and Innovation Fund of Hungary 2020-4.1.1-TKP2020 (Project No: TKP2020-IKA-08)New National Excellence Program of the Ministry for Innovation and Technology from the source of the National Research, Development and Innovation Fund ÚNKP-20-4-II-PTE-874Research grant of Medical School, University of Pécs KA-2019-12 and KA-2021-23
6 · The paper itself

Abstract

Transient receptor potential ankyrin 1 (TRPA1), a nonselective cation channel, contributes to several (patho)physiological processes. Smell loss is an early sign in several neurodegenerative disorders, such as multiple sclerosis, Parkinson's and Alzheimer's diseases; therefore, we focused on its role in olfaction and social behaviour with the aim to reveal its potential therapeutic use. The presence of

Indexed as

2-methyl-2-thiazolineinnate fearolfactory bulbolfactory epitheliumpiriform cortexsocial behaviourTRPA1valeric acid

Identifiers

PMID34959735
PMCPMC8703823
OpenAlexW4200291639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.