Evidence map›Paper›PMID 34959716›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

The Therapeutic Potential of Common Herbal and Nano-Based Herbal Formulations against Ovarian Cancer: New Insight into the Current Evidence.

Fatemeh Rezaei-Tazangi, Hossein Roghani-Shahraki, Mahdi Khorsand Ghaffari, Firoozeh Abolhasani Zadeh, Aynaz Boostan, Reza ArefNezhad, Hossein Motedayyen

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  11. New trends in diagnosing and treating ovarian cancer using nanotechnology.Frontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatemeh Rezaei-TazangiDepartment of Anatomy, School of Medicine, Fasa University of Medical Sciences, Fasa 7345149573, Iran.ORCID 0000-0003-1402-6482
Hossein Roghani-ShahrakiStudent Research Committee, Shiraz University of Medical Sciences, Shiraz 1433671348, Iran.ORCID 0000-0001-9530-5744
Mahdi Khorsand GhaffariDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz 1433671348, Iran.
Firoozeh Abolhasani ZadehDepartment of Surgery, Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
Aynaz BoostanDepartment of Obstetrics & Gynecology, Saveh Chamran Hospital, Saveh 3919676651, Iran.
Reza ArefNezhadDepartment of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz 1433671348, Iran.
Hossein MotedayyenAutoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan 8715973474, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OCa) is characterized as one of the common reasons for cancer-associated death in women globally. This gynecological disorder is chiefly named the "silent killer" due to lacking an association between disease manifestations in the early stages and OCa. Because of the disease recurrence and resistance to common therapies, discovering an effective therapeutic way against the disease is a challenge. According to documents, some popular herbal formulations, such as curcumin, quercetin, and resveratrol, can serve as an anti-cancer agent through different mechanisms. However, these herbal products may be accompanied by some pharmacological limitations, such as poor bioavailability, instability, and weak water solubility. On the contrary, using nano-based material, e.g., nanoparticles (NPs), micelles, liposomes, can significantly solve these limitations. Therefore, in the present study, we will summarize the anti-cancer aspects of these herbal and-nano-based herbal formulations with a focus on their mechanisms against OCa.

Indexed as

curcuminherbal medicinenanotechnologyquercetinresveratrol

Identifiers

PMID34959716
PMCPMC8705681

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.