Evidence map›Paper›PMID 34959615›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

An Overview of Cellulose Derivatives-Based Dressings for Wound-Healing Management.

Elena-Emilia Tudoroiu, Cristina-Elena Dinu-Pîrvu, Mădălina Georgiana Albu Kaya, Lăcrămioara Popa, Valentina Anuța, Răzvan Mihai Prisada, Mihaela Violeta Ghica

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 173 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elena-Emilia TudoroiuDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy Bucharest, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Cristina-Elena Dinu-PîrvuDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy Bucharest, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Mădălina Georgiana Albu KayaDepartment of Collagen, Division Leather and Footwear Research Institute, National Research and Development Institute for Textile and Leather, 93 Ion Minulescu Str., 031215 Bucharest, Romania.ORCID 0000-0001-9960-2244
Lăcrămioara PopaDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy Bucharest, 6 Traian Vuia Str., 020956 Bucharest, Romania.ORCID 0000-0002-3139-9865
Valentina AnuțaDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy Bucharest, 6 Traian Vuia Str., 020956 Bucharest, Romania.ORCID 0000-0003-1266-5862
Răzvan Mihai PrisadaDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy Bucharest, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Mihaela Violeta GhicaDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy Bucharest, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RONational Research & Development Institute for Textiles and Leather · RO

Funding

This paper was financially supported by the "Carol Davila" University of Medicine and Pharmacy through Contract No. CNFIS-FDI-2021-0300 and RDI Capability consolidation at the Institutional level of the multidisciplinary research teams involved in the sus Contract No. CNFIS-FDI-2021-0300
6 · The paper itself

Abstract

Presently, notwithstanding the progress regarding wound-healing management, the treatment of the majority of skin lesions still represents a serious challenge for biomedical and pharmaceutical industries. Thus, the attention of the researchers has turned to the development of novel materials based on cellulose derivatives. Cellulose derivatives are semi-synthetic biopolymers, which exhibit high solubility in water and represent an advantageous alternative to water-insoluble cellulose. These biopolymers possess excellent properties, such as biocompatibility, biodegradability, sustainability, non-toxicity, non-immunogenicity, thermo-gelling behavior, mechanical strength, abundance, low costs, antibacterial effect, and high hydrophilicity. They have an efficient ability to absorb and retain a large quantity of wound exudates in the interstitial sites of their networks and can maintain optimal local moisture. Cellulose derivatives also represent a proper scaffold to incorporate various bioactive agents with beneficial therapeutic effects on skin tissue restoration. Due to these suitable and versatile characteristics, cellulose derivatives are attractive and captivating materials for wound-healing applications. This review presents an extensive overview of recent research regarding promising cellulose derivatives-based materials for the development of multiple biomedical and pharmaceutical applications, such as wound dressings, drug delivery devices, and tissue engineering.

Indexed as

bioactive agents delivery systemscellulose derivativeswound dressingswound management

Identifiers

PMID34959615
PMCPMC8706040
OpenAlexW3216580765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.