ReviewPathogens (Basel, Switzerland)2021
Suitability of GWAS as a Tool to Discover SNPs Associated with Tick Resistance in Cattle: A Review.
Review in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Comprehensive evaluation of tick infestation dynamics and host response in Kankrej and Holstein Friesian crossbred cattle.Veterinary and animal science · 2026Article
- Potential Applications of Genome-Wide Association Studies in Establishing Climate Resilience in Livestock: A Comprehensive Review.International journal of molecular sciences · 2026Review
- Blood plasma proteomics for detecting potential biomarkers for tick resistance in a tropically adapted beef cattle breed.BMC genomics · 2025Article
- Application of Genomic Selection in Beef Cattle Disease Prevention.Animals : an open access journal from MDPI · 2025Review
- Genome-wide association study of the antibody response toArchives animal breeding · 2025Article
- Applying the algorithm for Proven and young in GWAS Reveals high polygenicity for key traits in Nellore cattle.Frontiers in genetics · 2025Article
- Exploring the biological responses involved in the genetic resistance to Rhipicephalus microplus in Argentine Creole cattle.Tropical animal health and production · 2024Article
- An overview of recent technological developments in bovine genomics.Veterinary and animal science · 2024Review
- Application of GWAS and mGWAS in Livestock and Poultry Breeding.Animals : an open access journal from MDPI · 2024Review
- Genome-Wide Association Study as an Efficacious Approach to Discover Candidate Genes Associated with Body Linear Type Traits in Dairy Cattle.Animals : an open access journal from MDPI · 2024Review
- Elucidation of novel SNPs affecting immune response to classical swine fever vaccination in pigs using immunogenomics approach.Veterinary research communications · 2024Article
- Current Status and Challenges Associated with Tick-Borne Pathogens and Diseases: Where Do We Stand?Pathogens (Basel, Switzerland) · 2023Article
- Tick and Tick-Borne Diseases: New Problems Providing New Possible Solutions.Pathogens (Basel, Switzerland) · 2023Article
- Vetinformatics from functional genomics to drug discovery: Insights into decoding complex molecular mechanisms of livestock systems in veterinary science.Frontiers in veterinary science · 2022Review
- Integrative QTL mapping and selection signatures in Groningen White Headed cattle inferred from whole-genome sequences.PloS one · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the biological mechanisms underlying tick resistance in cattle holds the potential to facilitate genetic improvement through selective breeding. Genome wide association studies (GWAS) are popular in research on unraveling genetic determinants underlying complex traits such as tick resistance. To date, various studies have been published on single nucleotide polymorphisms (SNPs) associated with tick resistance in cattle. The discovery of SNPs related to tick resistance has led to the mapping of associated candidate genes. Despite the success of these studies, information on genetic determinants associated with tick resistance in cattle is still limited. This warrants the need for more studies to be conducted. In Africa, the cost of genotyping is still relatively expensive; thus, conducting GWAS is a challenge, as the minimum number of animals recommended cannot be genotyped. These population size and genotype cost challenges may be overcome through the establishment of collaborations. Thus, the current review discusses GWAS as a tool to uncover SNPs associated with tick resistance, by focusing on the study design, association analysis, factors influencing the success of GWAS, and the progress on cattle tick resistance studies.
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