Evidence map›Paper›PMID 34959414›Full record

ArticlePharmaceutics2021

Assessment and Modeling of Plasmonic Photothermal Therapy Delivered via a Fiberoptic Microneedle Device Ex Vivo.

Forhad Akhter, Santiago Manrique-Bedoya, Chris Moreau, Andrea Lynn Smith, Yusheng Feng, Kathryn M Mayer, R Lyle Hood

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Forhad AkhterDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA.ORCID 0000-0002-5030-1632
Santiago Manrique-BedoyaDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA.
Chris MoreauGastroenterology and Transplant, UT Health San Antonio, San Antonio, TX 78229, USA.
Andrea Lynn SmithDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA.
Yusheng FengDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA.
Kathryn M MayerDepartment of Physics & Astronomy, University of Texas at San Antonio, San Antonio, TX 78249, USA.
R Lyle HoodDepartment of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmonic photothermal therapy (PPTT) has potential as a superior treatment method for pancreatic cancer, a disease with high mortality partially attributable to the currently non-selective treatment options. PPTT utilizes gold nanoparticles infused into a targeted tissue volume and exposed to a specific light wavelength to induce selective hyperthermia. The current study focuses on developing this approach within an ex vivo porcine pancreas model via an innovative fiberoptic microneedle device (FMD) for co-delivering light and gold nanoparticles. The effects of laser wavelengths (808 vs. 1064 nm), irradiances (20-50 mW·mm

Indexed as

bioheatCOMSOL tissue modelfiberoptic microneedlegold nanorodshyperthermianear infraredphotothermalplasmonic photothermal therapy

Identifiers

PMID34959414
PMCPMC8703536

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.