Evidence map›Paper›PMID 34959308›Full record

ArticlePharmaceutics2021

Silica Coating of Ferromagnetic Iron Oxide Magnetic Nanoparticles Significantly Enhances Their Hyperthermia Performances for Efficiently Inducing Cancer Cells Death In Vitro.

Cristian Iacoviță, Ionel Fizeșan, Stefan Nitica, Adrian Florea, Lucian Barbu-Tudoran, Roxana Dudric, Anca Pop, Nicoleta Vedeanu, Ovidiu Crisan, Romulus Tetean and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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  14. Hope for bone regeneration: The versatility of iron oxide nanoparticles.Frontiers in bioengineering and biotechnology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Cristian IacovițăDepartment of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 6 Pasteur St., 400349 Cluj-Napoca, Romania.
Ionel FizeșanDepartment of Toxicology, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 6A Pasteur St., 400349 Cluj-Napoca, Romania.
Stefan NiticaDepartment of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 6 Pasteur St., 400349 Cluj-Napoca, Romania.
Adrian FloreaDepartment of Cell and Molecular Biology, Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, 6 Pasteur St., 400349 Cluj-Napoca, Romania.ORCID 0000-0002-0898-7626
Lucian Barbu-TudoranElectron Microscopy Center "Prof. C. Craciun", Faculty of Biology & Geology, "Babes-Bolyai" University, 5-7 Clinicilor St., 400006 Cluj-Napoca, Romania.ORCID 0000-0003-0360-016X
Roxana DudricFaculty of Physics, "Babes Bolyai" University, Kogalniceanu 1, 400084 Cluj-Napoca, Romania.
Anca PopDepartment of Toxicology, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 6A Pasteur St., 400349 Cluj-Napoca, Romania.ORCID 0000-0001-5375-6053
Nicoleta VedeanuDepartment of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 6 Pasteur St., 400349 Cluj-Napoca, Romania.
Ovidiu CrisanDepartment of Organic Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babes St., 400012 Cluj-Napoca, Romania.
Romulus TeteanFaculty of Physics, "Babes Bolyai" University, Kogalniceanu 1, 400084 Cluj-Napoca, Romania.
Felicia LoghinDepartment of Toxicology, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 6A Pasteur St., 400349 Cluj-Napoca, Romania.
Constantin Mihai LucaciuDepartment of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 6 Pasteur St., 400349 Cluj-Napoca, Romania.ORCID 0000-0002-9385-3568
Iuliu Hațieganu University of Medicine and Pharmacy · ROBabeș-Bolyai University · RO

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P1-1.1-PD-2019-0804Unitatea Executiva Pentru Finantarea Invatamantului Superior Si A Cercetarii Stiintifice Universitare PN-III-P2-2.1-PED-2019-3283
6 · The paper itself

Abstract

Increasing the biocompatibility, cellular uptake, and magnetic heating performance of ferromagnetic iron-oxide magnetic nanoparticles (F-MNPs) is clearly required to efficiently induce apoptosis of cancer cells by magnetic hyperthermia (MH). Thus, F-MNPs were coated with silica layers of different thicknesses via a reverse microemulsion method, and their morphological, structural, and magnetic properties were evaluated by multiple techniques. The presence of a SiO

Indexed as

A35A549alamar blueBJcancer cellsiron oxide magnetic nanoparticlesmagnetic hyperthermianeutral redsilica coating

Identifiers

PMID34959308
PMCPMC8706665
OpenAlexW3214972746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.