ReviewPharmaceutics2021
Antimicrobial Photodynamic Therapy: Latest Developments with a Focus on Combinatory Strategies.
Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 2 syntheses or guidelines pooled it, 162 citations in OpenAlex.
- Photodithazine-Mediated Antimicrobial Photodynamic Therapy: A Systematic Review of Efficacy and Applications.International journal of molecular sciences · 2025Pooled it
- Evaluating the Efficacy of Rose Bengal as a Photosensitizer in Antimicrobial Photodynamic Therapy AgainstInternational journal of molecular sciences · 2025Pooled it
- Antibiotic-Free Strategies for Managing Antimicrobial-Resistant Infections.Pharmaceutics · 2026Review
- Comparative evaluation of photosensitizers nitrogen-doped graphene quantum dots and indocyanine green againstJournal of conservative dentistry and endodontics · 2026Article
- From Simulation to Therapy: Light Guidance Through Zirconium Dental Implants for Bone-Targeted Photodynamic Inactivation.Bioengineering (Basel, Switzerland) · 2026Article
- Protonated Defect-Engineered Carbon Nitride Enables Bio-Interface-Enhanced Photodynamic Antibacterial Activity with Potential Periodontal Application.Materials (Basel, Switzerland) · 2026Article
- Red-Emissive Azure A-Derived Carbon Dots with Semi-Ordered spACS omega · 2026Article
- Surface modification and nanodelivery of hypocrellin-based photosensitizers: photophysical optimization and biomedical applications.Journal of nanobiotechnology · 2026Review
- Antibacterial activity and mechanism of rutin in UV‑A light treatment against Escherichia coli O157:H7.Archives of microbiology · 2026Article
- Selective Photodisinfection of Bacteria and Biofilms Using Blue Light-Activated Molybdenum Nanoclusters via Dual Singlet Oxygen and Hydroxyl Radical Sensitization.Inorganic chemistry · 2026Article
- Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review).Molecular medicine reports · 2026Review
- Article
- Exploiting endogenous Protoporphyrin IX for Photodynamic inactivation of Pseudomonas aeruginosa.Journal of fluorescence · 2026Article
- Carbon Dot-Based Photodynamic Therapy for Clinical Treatment of Nonmelanoma Skin Cancer.Dermatology practical & conceptual · 2026Article
- Graphene-Based 3D Scaffolds in Bone Regeneration: Emerging Opportunities for MRONJ Treatment.Pharmaceutics · 2026Review
- The photodynamic inactivation in the control of the seafood zoonotic parasite, Anisakis sp.Parasitology research · 2026Article
- Colistin Resistance: From Laboratory Research to Modern Clinical Management.Antibiotics (Basel, Switzerland) · 2026Review
- Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026Review
- Bioceramic bone tissue-engineered substitutes with anti-inflammatory effects in periodontitis.Frontiers in bioengineering and biotechnology · 2026Review
- Photodynamic therapy with methylene blue effectively kills antibiotic resistant bacteria from pediatric patients with perforated appendicitis.Scientific reports · 2025Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the numerous possibilities to combine aPDT with other antimicrobial treatments to combat localized infections. After revisiting the basic principles of aPDT, this review first highlights the current state of the art of curative or preventive aPDT applications with relevant clinical trials. In addition, the most recent developments in photochemistry and photophysics as well as advanced carrier systems in the context of aPDT are provided, with a focus on the latest generations of efficient and versatile PSs and the progress towards hybrid-multicomponent systems. In particular, deeper insight into combinatory aPDT approaches is afforded, involving non-radiative or other light-based modalities. Selected aPDT perspectives are outlined, pointing out new strategies to target and treat microorganisms. Finally, the review works out the evolution of the conceptually simple PDT methodology towards a much more sophisticated, integrated, and innovative technology as an important element of potent antimicrobial strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.