Evidence map›Paper›PMID 34958984›Full record

ArticlePractical radiation oncology

Use of Specific Duodenal Dose Constraints During Treatment Planning Reduces Toxicity After Definitive Paraaortic Radiation Therapy for Cervical Cancer.

David S Lakomy, Juliana Wu, Bhavana V Chapman, Zhiqian Henry Yu, Belinda Lee, Ann H Klopp, Anuja Jhingran, Patricia J Eifel, Lilie L Lin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Practical radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

David S LakomyDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Dartmouth Geisel School of Medicine, Hanover, New Hampshire.
Juliana WuDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; The University of Texas School of Public Health, Houston, Texas.
Bhavana V ChapmanDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Zhiqian Henry YuDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Belinda LeeDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Ann H KloppDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Anuja JhingranDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Patricia J EifelDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Lilie L LinDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: LLLin@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USDartmouth College · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

purposeThis study aimed to validate the safety of paraaortic nodal (PAN) radiation therapy (RT) for patients with cervical cancer when the duodenal dose is limited to V METHODS AND MATERIALS: A total of 97 patients who were treated with RT for cervical cancer between 2010 and 2018 received at least 56 Gy to grossly involved PANs. Patients were treated with concurrent chemoradiation (n = 88; 91%), with 93% of patients (n = 90) receiving intensity modulated RT to the initial PAN field and 98% (n = 95) receiving intensity modulated RT to a sequential PAN boost. The V

resultsThe median duodenal V

conclusionsLimiting the duodenal dose to V

Indexed as

Radiotherapy, Intensity-ModulatedUterine Cervical NeoplasmsChemoradiotherapyConstriction, PathologicDuodenumFemaleHumansRadiotherapy Dosage

Identifiers

PMID34958984
PMCPMC9552869
OpenAlexW4200286387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.