SynthesisBJS open2021
Surgical treatment of anorectal melanoma: a systematic review and meta-analysis.
Synthesis in BJS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 36 citations in OpenAlex.
- Primary anorectal melanotic melanoma: a case report.Journal of medical case reports · 2026Article
- A case of anal melanoma treated with wide local excision and doublet immunotherapy.Journal of surgical case reports · 2026Article
- Comparison of survival outcomes between local excision and radical resection in patients with rectal mucosal melanoma.World journal of surgical oncology · 2026Article
- Detection and surgical intervention in anorectal malignant melanoma: a case report.Journal of medical case reports · 2026Article
- Rectal melanoma: managing a rare cause of rectal bleeding: case report and review of the literature.World journal of surgical oncology · 2026Review
- Early diagnosis and delayed treatment of anorectal melanoma in a 19-year-old female: A case report.International journal of surgery case reports · 2025Article
- Case Report: Surgical management and prognostic factors in primary anorectal melanoma: a retrospective analysis of nine cases.Frontiers in medicine · 2025Article
- Case Report: Surgery combined with targeted therapy for metastatic anorectal malignant mucosal melanoma.Frontiers in oncology · 2025Article
- Case Report: S100-negative primary anorectal melanoma with elevated Ki67: a case for biology-driven radical resection despite early radiological staging.Frontiers in oncology · 2025Article
- Long term survival following cryoablation with adjuvant Toripalimab for anorectal malignant melanoma: a case report.Frontiers in oncology · 2025Article
- Successful multimodality treatment of anorectal melanoma after wide local excision: a case report.Frontiers in oncology · 2025Article
- A rare account of incidentally discovered anal melanoma.Journal of surgical case reports · 2024Article
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- Surgical approach of anorectal mucosal melanoma with locoregional disease - a case report.Journal of surgical case reports · 2024Article
- Beyond squamous cell carcinoma: MRI appearance of uncommon anal neoplasms and mimickers.Abdominal radiology (New York) · 2023Review
- Primary anorectal melanoma mimicking polyp in a scleroderma patient: a case report.Annals of medicine and surgery (2012) · 2023Article
- Treatment outcomes and prognostic factors in 47 patients with primary anorectal malignant melanoma in the immune therapy era.Journal of cancer research and clinical oncology · 2023Article
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- Management of primary anorectal mucosal melanoma during the COVID-19 pandemic.Ecancermedicalscience · 2023Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnorectal melanoma is a rare neoplasm with a poor prognosis. The surgical approaches for anorectal melanoma can be categorized into local excision (procedures without lymph node removal and preservation of the rectum) and extensive resection (procedures with rectum and pararectal lymph node removal). The aim of this systematic review and meta-analysis was to compare the survival of patients who underwent extensive resection with that of patients who underwent local excision, stratifying patients according to tumour stage.
methodsA literature review was performed according to PRISMA guidelines by searching MEDLINE/PubMed for manuscripts published until March 2021. Studies comparing survival outcomes in patients with anorectal melanoma who underwent local excision versus extensive resection were screened for eligibility. Meta-analysis was performed for overall survival after the different surgical approaches, stratified by tumour stage.
resultsThere were 347 studiesidentified of which 34 were included for meta-analysis with a total of 1858 patients. There was no significant difference in overall survival between the surgical approaches in patients per stage (stage I odds ratio 1.30 (95 per cent c.i. 0.62 to 2.72, P = 0.49); stage II odds ratio 1.61 (95 per cent c.i. 0.62 to 4.18, P = 0.33); stage I-III odds ratio 1.19 (95 per cent c.i. 0.83 to 1.70, P = 0.35). Subgroup analyses were conducted for the time intervals (<2000, 2001-2010 and 2011-2021) and for continent of study origin. Subgroup analysis for time interval and continent of origin also showed no statistically significant differences in overall survival.
conclusionNo significant survival benefit exists for patients with anorectal melanoma treated with local excision or extensive resection, independent of tumour stage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.