ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2022
Scaffolding layered control architectures through constraint closure: insights into brain evolution and development.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Synthesizing the temporal self: robotic models of episodic and autobiographical memory.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Entropy and Cross-Level Orderliness in Light of the Interconnection between the Neural System and Consciousness.Entropy (Basel, Switzerland) · 2023Review
- Comparing the development of cortex-wide gene expression patterns between two species in a common reference frame.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Biological action at a distance: Correlated pattern formation in adjacent tessellation domains without communication.PLoS computational biology · 2022Article
- Neuroscience needs evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
The functional organization of the mammalian brain can be considered to form a layered control architecture, but how this complex system has emerged through evolution and is constructed during development remains a puzzle. Here we consider brain organization through the framework of constraint closure, viewed as a general characteristic of living systems, that they are composed of multiple sub-systems that constrain each other at different timescales. We do so by developing a new formalism for constraint closure, inspired by a previous model showing how within-lifetime dynamics can constrain between-lifetime dynamics, and we demonstrate how this interaction can be generalized to multi-layered systems. Through this model, we consider brain organization in the context of two major examples of constraint closure-physiological regulation and visual orienting. Our analysis draws attention to the capacity of layered brain architectures to scaffold themselves across multiple timescales, including the ability of cortical processes to constrain the evolution of sub-cortical processes, and of the latter to constrain the space in which cortical systems self-organize and refine themselves. This article is part of the theme issue 'Systems neuroscience through the lens of evolutionary theory'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.