Evidence map›Paper›PMID 34957809›Full record

ArticleReviews in cardiovascular medicine2021

Racial differences in cardiopulmonary outcomes of hospitalized COVID-19 patients with acute kidney injury.

Obiora Egbuche, Temidayo Abe, Shirley I Nwokike, Opeyemi Jegede, Kenechukwu Mezue, Titilope Olanipekun, Ifeoma Onuorah, Melvin R Echols

Open access · goldAbstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Obiora EgbucheDivision of Cardiovascular Medicine, Ohio State University, Columbus, OH 43210, USA.
Temidayo AbeDepartment of Internal Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Shirley I NwokikeDepartment of Internal Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
Opeyemi JegedeDepartment of Biostatistics and Epidemiology, University of North Texas Health Science Center, Fort-Worth, TX 76107, USA.
Kenechukwu MezueDivision of Nuclear Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Titilope OlanipekunDepartment of Hospital Medicine, Covenant Health System, Knoxville, TN 37902, USA.
Ifeoma OnuorahDivision of Cardiovascular Disease, Emory University School of Medicine, Atlanta, GA 30322, USA.
Melvin R EcholsDivision of Cardiovascular Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Morehouse School of Medicine · USAugusta University · USCovenant Health System · USEmory University · USHarvard University · USThe Ohio State University · USUniversity of North Texas Health Science Center · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Institutional Career Development CoreKL2TR002381 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Anandi Nayan Sheth · 2017 to 2026
$14.1M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
NCATS NIH HHS KL2 TR002381NCATS NIH HHS UL1 TR002378NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

In-hospital acute kidney injury (IH-AKI) has been reported in a significant proportion of patients with COVID-19 and is associated with increased disease burden and poor outcomes. However, the mechanisms of injury are not fully understood. We sought to determine the significance of race on cardiopulmonary outcomes and in-hospital mortality of hospitalized COVID-19 patients with AKI. We conducted a retrospective cohort study of consecutive patients hospitalized in Grady Health System in Atlanta, Georgia between February and July 2020, who tested positive for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) on qualitative polymerase-chain-reaction assay. We evaluated the primary composite outcome of in-hospital cardiac events, and mortality in blacks with AKI versus non-blacks with AKI. In a subgroup analysis, we evaluated the impact of AKI in all blacks and in all non-blacks. Of 293 patients, effective sample size was 267 after all exclusion criteria were applied. The mean age was 61.4 ± 16.7, 39% were female, and 75 (28.1%) had IH-AKI. In multivariable analyses, blacks with IH-AKI were not more likely to have in-hospital cardiac events (aOR 0.3, 95% Confidence interval (CI) 0.04-1.86,

Indexed as

Acute Kidney InjuryCOVID-19AdultAgedFemaleHospital MortalityHumansMiddle AgedRace FactorsRetrospective StudiesRisk FactorsSARS-CoV-2AKIBlack raceCardiac eventsCOVID-19Mortality

Identifiers

PMID34957809
PMCPMC9054458
OpenAlexW4200195888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.