Evidence map›Paper›PMID 34957520›Full record

ArticleThe Journal of antimicrobial chemotherapy2022

Point prevalence survey of antibiotic use in hospitals in Latin American countries.

Gabriel Levy Hara, Robin Rojas-Cortés, Helvert Felipe Molina León, Anahí Dreser Mansilla, Ismary Alfonso Orta, José Noe Rizo-Amezquita, René Guillermo Santos Herrera, Silvia Mendoza de Ayala, Marlen Arce Villalobos, Hilda Mantilla Ponte and 6 more

Erratum issuedAbstract read
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama.Revista panamericana de salud publica = Pan American journal of public health · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Gabriel Levy HaraHospital Durand, Buenos Aires, Argentina.
Robin Rojas-CortésPan American Health Organization/World Health Organization, Washington, DC, USA.
Helvert Felipe Molina LeónPan American Health Organization/World Health Organization, Washington, DC, USA.
Anahí Dreser MansillaInstituto de Salud Pública, Cuernavaca, México.
Ismary Alfonso OrtaCentro para el Control Estatal de Medicamentos, Equipos y Dispositivos Médicos, Ciudad Habana, Cuba.
José Noe Rizo-AmezquitaComisión Nacional de Arbitraje Médico, Ciudad de México, México.
René Guillermo Santos HerreraDirección Nacional de Enfermedades Infecciosas, Ministerio de Salud, San Salvador, El Salvador.
Silvia Mendoza de AyalaInstituto Salvadoreño del Seguro Social, San Salvador, El Salvador.
Marlen Arce VillalobosDirección Vigilancia de la Salud, Ministerio de Salud, San José, Costa Rica.
Hilda Mantilla PonteDirección General de Medicamentos, Insumos y Drogas, Ministerio de Salud, Lima, Perú.
Ever DavilaDivisión General de Insumos Médicos, Ministerio de Salud, Managua, Nicaragua.
Gloria AguilarInstituto Regional de Investigación en Salud, Universidad Nacional de Caaguazú, Coronel Oviedo, Paraguay.
Analía PorrásPan American Health Organization/World Health Organization, Washington, DC, USA.
Pilar Ramón-PardoPan American Health Organization/World Health Organization, Washington, DC, USA.
José Luis CastroPan American Health Organization/World Health Organization, Washington, DC, USA.
Latin American Point Prevalent Survey Study Group

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundPoint prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals.

methodsAn adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCap©) through a mobile device was used for data collection.

resultsBetween December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6% received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3% of cases.

conclusionsAntibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.

Indexed as

Anti-Bacterial AgentsCross InfectionHospitalsHumansLatin AmericaPrevalenceAnti-Bacterial Agents

Identifiers

PMID34957520
PMCPMC9092443

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.