Evidence map›Paper›PMID 34957430›Full record

ArticleCardiovascular digital health journal2021

Neural networks applied to 12-lead electrocardiograms predict body mass index, visceral adiposity and concurrent cardiometabolic ill-health.

Xinyang Li, Kiran Haresh Kumar Patel, Lin Sun, Nicholas S Peters, Fu Siong Ng

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular digital health journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xinyang LiNational Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom.
Kiran Haresh Kumar PatelNational Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom.
Lin SunNational Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom.
Nicholas S PetersNational Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom.
Fu Siong NgNational Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom.
Imperial College London · GB

Funding

British Heart Foundation RG/16/3/32175Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

backgroundObesity is associated with electrophysiological remodeling, which manifests as detectable changes on the surface electrocardiogram (ECG).

objectiveTo develop neural networks (NN) to predict body mass index (BMI) from ECGs and test the hypothesis that discrepancies between NN-predicted BMI and measured BMI are indicative of underlying adiposity and/or concurrent cardiometabolic ill-health.

methodsNN models were developed using 36,856 12-lead resting ECGs from the UK Biobank. Two architectures were developed for continuous and categorical BMI estimation (normal weight [BMI <25 kg/m

resultsECGs were available for 17,807 male and 19,049 female participants (mean ages: 61 ± 7 and 63 ± 8 years; mean BMI 26 ± 5 kg/m

conclusionNN models applied to 12-lead ECGs predict BMI with a reasonable degree of accuracy. Discrepancies between NN-predicted and calculated BMI may be indicative of underlying visceral adiposity and concomitant cardiometabolic perturbation, which could be used to identify individuals at risk of cardiometabolic disease.

Indexed as

12-Lead ECGAdiposityCardiometabolicNeural networksObesity

Identifiers

PMID34957430
PMCPMC8669785
OpenAlexW3206292578

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.