Evidence map›Paper›PMID 34957142›Full record

ArticleFrontiers in medicine2021

Chest Imaging in the Diagnosis and Management of Pulmonary Tuberculosis: The Complementary Role of Thoraci Ultrasound.

Gaetano Rea, Marco Sperandeo, Roberta Lieto, Marialuisa Bocchino, Carla Maria Irene Quarato, Beatrice Feragalli, Tullio Valente, Giulia Scioscia, Ernesto Giuffreda, Maria Pia Foschino Barbaro and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06409780 (Comparative Efficacy of Chest Ultrasound, Chest X-Ray and Computer-aided Diagnostic), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06409780 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Comparative Efficacy of Chest Ultrasound, Chest X-Ray and Computer-aided Diagnostic (CAD) for Tuberculosis Diagnosis in Low-Resource Setting: A Cross-Sectional Study From Ethiopia (CUSTB)

TypeinterventionalSponsorUniversity of BariRan2024 to 2025Enrolled136ConditionsTuberculosis, PulmonaryArmsComparative analysis of CUS, CAD and CXR in pulmonary TB
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Gaetano ReaDepartment of Radiology, Azienda Ospedaliera dei Colli-Cotugno and Monaldi Hospital, Naples, Italy.
Marco SperandeoDepartment of Medical Sciences, Unit of Interventional and Diagnostic Ultrasound of Internal Medicine, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Roberta LietoDepartment of Radiology, Azienda Ospedaliera dei Colli-Cotugno and Monaldi Hospital, Naples, Italy.
Marialuisa BocchinoRespiratory Medicine Unit, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Carla Maria Irene QuaratoDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, Foggia, Italy.
Beatrice FeragalliDepartment of Medical, Oral and Biotechnological Sciences - Radiology Unit "G. D'Annunzio", University of Chieti-Pescara, Chieti, Italy.
Tullio ValenteDepartment of Radiology, Azienda Ospedaliera dei Colli-Cotugno and Monaldi Hospital, Naples, Italy.
Giulia SciosciaDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, Foggia, Italy.
Ernesto GiuffredaDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, Foggia, Italy.
Maria Pia Foschino BarbaroDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, Foggia, Italy.
Donato LacedoniaDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, Foggia, Italy.
University of Foggia · ITOspedale Monaldi · ITFederico II University Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is a severe infectious disease that still represents a major cause of mortality and morbidity worldwide. For these reasons, clinicians and radiologists should use all the available diagnostic tools in the assessment of the disease in order to provide precise indications about starting an anti-tubercular treatment and reduce risk of TB transmission and complications especially in developing countries where the disease is still endemic. As TB mycobacteria are mainly transmitted through respiratory droplets, the pulmonary parenchyma is usually the first site of infection. As a result, chest imaging plays a central role in the diagnostic process. Thoracic ultrasound (TUS) is a portable, non-invasive, radiation-free, and cost-contained technology which could be easily available in resource-limited settings. This perspective article focuses on the potential role of TUS in the diagnosis and management of patients with pulmonary TB. Unfortunately, there are still insufficient evidence and too contrasting data to judge TUS as an appropriate diagnostic method for the screening of the disease. Despite this, TUS may have a useful role in identifying pleural and anterior pericardial effusions or in the identification of abscesses of the anterior chest wall and paraspinal collections in low- and middle-income settings. In addition, TUS seems to have a milestone role in guiding minimally invasive interventional procedures, such as placement of chest tubes, drainage of loculated collections, thoracentesis and pericardiocentesis, and percutaneous biopsy of subpleural pulmonary consolidations or pleural plaques.

Indexed as

chest computed tomography (chest CT)chest imagingchest X-ray (CXR)diagnosis and managementpulmonary tuberculosisthoracic ultrasound (TUS)

Identifiers

PMID34957142
PMCPMC8703038
OpenAlexW4200305524

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.