Evidence map›Paper›PMID 34956621›Full record

ArticleToxicology research2021

Toxicity evaluation in rats following 28 days of inhalation exposure to xylitol aerosol.

Yushan Tian, Hongjuan Wang, Huan Chen, Xianmei Li, Fengjun Lu, Shuhao Ma, Wenming Wang, Jia Wu, Jiayou Tang, Pengxia Feng and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Yushan TianChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Hongjuan WangChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Huan ChenChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Xianmei LiChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Fengjun LuChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Shuhao MaChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Wenming WangChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Jia WuChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Jiayou TangChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Pengxia FengChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Yaning FuChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Shulei HanChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Tong LiuChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
Hongwei HouChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.ORCID https://orcid.org/0000-0001-9389-4928
Qingyuan HuChina National Tobacco Quality Supervision and Test Center, Zhengzhou, PR China.
China Tobacco · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xylitol has reported to decrease gingival inflammation and nasopharyngeal pneumonia, which indicated that xylitol may have potential application in respiratory diseases. Although some studies have reported the inhalation toxicity of xylitol, however, the longest period tested was only for 14 days. The inhalation toxicity of xylitol is insufficient. This work investigated the potential subacute toxicity of xylitol according to the OECD TG 412. Rats were randomly divided into a control group and different dosage groups (2 g/m

Indexed as

aerosol inhalationNOAECsubacute toxicityxylitol

Identifiers

PMID34956621
PMCPMC8692747
OpenAlexW3217288091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.