Evidence map›Paper›PMID 34956611›Full record

ArticleInterface focus2022

Characteristics of respiratory microdroplet nuclei on common substrates.

Alexandros Kosmidis-Papadimitriou, Shaojun Qi, Ophelie Squillace, Nicole Rosik, Mark Bale, Peter J Fryer, Zhenyu J Zhang

Open access · hybridAbstract read
In one paragraph

Article in Interface focus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexandros Kosmidis-PapadimitriouSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0002-1654-4630
Shaojun QiSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Ophelie SquillaceSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0003-3840-5065
Nicole RosikSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Mark BaleDoDxAct Ltd, Wells BA5 2LW, UK.
Peter J FryerSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0003-4767-7839
Zhenyu J ZhangSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0003-0243-2109
University of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the role of common substrates in the transmission of respiratory viruses, in particular SARS-CoV-2, uniformly distributed microdroplets (approx. 10 µm diameter) of artificial saliva were generated using an advanced inkjet printing technology to replicate the aerosol droplets and subsequently deposited on five substrates, including glass, polytetrafluoroethylene, stainless steel, acrylonitrile butadiene styrene and melamine. The droplets were found to evaporate within a short timeframe (less than 3 s), which is consistent with previous reports concerning the drying kinetics of picolitre droplets. Using fluorescence microscopy and atomic force microscopy, we found that the surface deposited microdroplet nuclei present two distinctive morphological features as the result of their drying mode, which is controlled by both interfacial energy and surface roughness. Nanomechanical measurements confirm that the nuclei deposited on all substrates possess similar surface adhesion (approx. 20 nN) and Young's modulus (approx. 4 MPa), supporting the proposed core-shell structure of the nuclei. We suggest that appropriate antiviral surface strategies, e.g. functionalization, chemical deposition, could be developed to modulate the evaporation process of microdroplet nuclei and subsequently mitigate the possible surface viability and transmissibility of respiratory virus.

Indexed as

microdropletnucleirespiratorysubstratestransmissionvirus

Identifiers

PMID34956611
PMCPMC8662393
OpenAlexW3164778327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.