Evidence map›Paper›PMID 34956564›Full record

ReviewJournal of healthcare engineering2021

The Potential Mechanism of Exercise Combined with Natural Extracts to Prevent and Treat Postmenopausal Osteoporosis.

Tongxi Zhou, Zhuo Gai, Xing Gao, Li Li

RetractedOpen access · hybridAbstract readReviewRetracted Publication
In one paragraph

Review in Journal of healthcare engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Total Flavonoids Isolated from the Leaves ofCurrent pharmaceutical design · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Efficacy and Mechanisms of Oleuropein in Postmenopausal Osteoporosis.Computational and mathematical methods in medicine · 2022
    Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tongxi ZhouCollege of Sports and Human Sciences, Harbin Sport University, Harbin 150008, Heilongjiang, China.
Zhuo GaiCollege of Sports and Human Sciences, Harbin Sport University, Harbin 150008, Heilongjiang, China.
Xing GaoCollege of Sports and Human Sciences, Harbin Sport University, Harbin 150008, Heilongjiang, China.
Li LiCollege of Sports and Human Sciences, Harbin Sport University, Harbin 150008, Heilongjiang, China.ORCID 0000-0002-8496-4573
Harbin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postmenopausal osteoporosis (PMOP) is a systemic chronic bone metabolic disease caused by the imbalance between bone formation and bone resorption mediated by estrogen deficiency. Both exercise and natural extracts are safe and effective means to prevent and control PMOP. The additive effect of exercise synergy extract against PMOP may be no less than that of traditional medicine. However, the mechanism of action of this method has not been clarified in detail. A large number of studies have shown that the pathogenesis of PMOP mainly involves the OPG-RANKL-RANK system, inflammation, and oxidative stress. Based on the abovementioned approaches, the present study reviews the anti-PMOP effects and mechanisms of exercise and natural extracts. Finally, it aims to explore the possibility of the target of the two combined anti-PMOP through this approach, thereby providing a new perspective for joint intervention research and providing a new direction for the treatment strategy of PMOP.

Indexed as

Osteoporosis, PostmenopausalBone DensityExerciseFemaleHumansPlant ExtractsPlant Extracts

Identifiers

PMID34956564
PMCPMC8709765
OpenAlexW4200249334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.