Evidence map›Paper›PMID 34956494›Full record

ArticleAmerican journal of translational research2021

Peripheral blood lymphocyte counts in patients with infectious mononucleosis or chronic active Epstein-Barr virus infection and prognostic risk factors of chronic active Epstein-Barr virus infection.

Jiancheng Lin, Xiaokang Chen, Haiming Wu, Xiaoyun Chen, Xiaomei Hu, Jin Xu

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jiancheng LinDepartment of Clinical Laboratory, Children's Hospital of Xiamen (Children's Hospital of Fudan University at Xiamen) Xiamen 361006, Fujian Province, China.
Xiaokang ChenDepartment of Clinical Laboratory, Children's Hospital of Xiamen (Children's Hospital of Fudan University at Xiamen) Xiamen 361006, Fujian Province, China.
Haiming WuDepartment of Clinical Laboratory, Children's Hospital of Xiamen (Children's Hospital of Fudan University at Xiamen) Xiamen 361006, Fujian Province, China.
Xiaoyun ChenDepartment of Clinical Laboratory, Children's Hospital of Xiamen (Children's Hospital of Fudan University at Xiamen) Xiamen 361006, Fujian Province, China.
Xiaomei HuDepartment of Clinical Laboratory, Children's Hospital of Xiamen (Children's Hospital of Fudan University at Xiamen) Xiamen 361006, Fujian Province, China.
Jin XuDepartment of Clinical Laboratory, Children's Hospital of Fudan University Shanghai 201102, China.
Children’s Hospital of Fudan University Xiamen Branch · CNChildren's Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the peripheral blood lymphocyte counts and analyze the prognostic risk factors for the death in patients with chronic active Epstein-Barr virus (CAEBV) infection.

methodsClinical data of 64 patients infected with CAEBV (CAEBV group) and 64 patients with infectious mononucleosis (IM group) in our hospital were retrospectively analyzed. Meanwhile, 64 healthy individuals came for physical examination were enrolled in the control group. The three groups were compared for white blood cell count, lymphocyte count, and levels of peripheral blood NK cells, B cells, CD3

resultsCompared with the control group, the IM group had higher levels of white blood cell count, lymphocyte count, CD3

conclusionPatients infected with CAEBV showed imbalance of lymphocyte subsets and immune dysfunction. EBV DNA>105 copies/mL, platelet count <50×10

Indexed as

Chronic active Epstein-Barr viruslymphocyte subsetsperipheral bloodprognosis

Identifiers

PMID34956494
PMCPMC8661241
OpenAlexW4206867313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.