Evidence map›Paper›PMID 34956433›Full record

SynthesisPain research & management

Anterior Cervical Discectomy and Fusion Using Zero-P System for Treatment of Cervical Spondylosis: A Meta-Analysis.

Zhaoyang Guo, Xiaolin Wu, Shuai Yang, Chang Liu, Youfu Zhu, Nana Shen, Zhu Guo, Weiliang Su, Yan Wang, Bohua Chen and 1 more

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Pain research & management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Review
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  12. Outcomes of different zero-profile spacers in the treatment of two-level cervical degenerative disk disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhaoyang GuoDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-3869-4170
Xiaolin WuDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-6200-7000
Shuai YangDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0003-1933-4484
Chang LiuDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0003-3085-4202
Youfu ZhuDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0003-3529-4187
Nana ShenDepartment of Rehabilitation, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-2137-3733
Zhu GuoDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-6044-5357
Weiliang SuDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0003-0784-8971
Yan WangDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-6460-9160
Bohua ChenDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-5400-4352
Hongfei XiangDepartment of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao 266003, China.ORCID https://orcid.org/0000-0002-5026-5918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe current study aimed to explore the efficacy of Zero profile intervertebral fusion system (Zero-P) and traditional anterior plate cage system (PC) in the treatment of cervical spondylotic myelopathy (CSM). Further, the present study evaluated effects of the treatments on medical security, height of intervertebral disc, adjacent-level ossification development (ALOD), and adjacent segmentation disease (ASD) through a systematic retrospective analysis.

methodsStudies on Zero-P system and traditional anterior plate cage system for ACDF in the treatment of CSM were searched in PubMed, Web of Science, Ovid, Embase, and Cochrane Library databases. Two independent researchers screened articles, extracted data, and evaluated the quality of the articles based on the inclusion and exclusion criteria of the current study. RevMan5.3 software was used for meta-analysis following the guidelines of Cochrane collaboration network. Cervical curvature, interbody fusion rate, preoperative and postoperative disc height index (DHI), fusion cage sinking rate, postoperative dysphagia, ASD, ALOD, and loosening of screw were compared between the two groups.

resultsA total of 17 literatures were included in the present study, including 6 randomized controlled trials and 11 observational studies. The studies comprised a total of 1204 patients with CSM, including 605 patients in the Zero-P system group (Zero-P group) and 599 patients in the traditional animal plate cage group (PC group). Results of this meta-analysis showed that postoperative dysphagia [OR = 0.40, CI (0.28, 95% 0.58),

conclusionIt was evident that the Zero-P system used in ACDF is superior compared with the traditional anterior plate cage system in postoperative dysphagia, avoiding ALOD, ASD, and screw loosening.

Indexed as

Spinal FusionSpondylosisCervical VertebraeDiskectomyHumansRandomized Controlled Trials as TopicRetrospective StudiesTreatment Outcome

Identifiers

PMID34956433
PMCPMC8702348

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.