Evidence map›Paper›PMID 34956376›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Dihydroartemisinin Promoted Bone Marrow Mesenchymal Stem Cell Homing and Suppressed Inflammation and Oxidative Stress against Prostate Injury in Chronic Bacterial Prostatitis Mice Model.

Shen Li, Yongzhang Li, Xiaozhe Su, Aiyun Han, Yang Cui, Shuyue Lv, Jin Zhang, Chao Li

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shen LiDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0003-1555-7584
Yongzhang LiDepartment of Urology, Hebei Province of Chinese Medicine, Shijiazhuang 050011, Hebei, China.ORCID https://orcid.org/0000-0002-6249-5198
Xiaozhe SuDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0002-7051-6032
Aiyun HanDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0003-4432-7366
Yang CuiDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0001-8393-9133
Shuyue LvDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0002-6635-9070
Jin ZhangDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0001-9550-5316
Chao LiDepartment of Urology, Shijiazhuang City People's Hospital, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0002-0587-7421
First Hospital of Shijiazhuang · CNHebei University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although bone marrow mesenchymal stem cells (BMMSCs) are effective in treating chronic bacterial prostatitis (CBP), the homing of BMMSCs seems to require ultrasound induction. Dihydroartemisinin (DHA) is an important derivative of artemisinin (ART) and has been previously reported to alleviate inflammation and autoimmune diseases. But the effect of DHA on chronic prostatitis (CP) is still unclear. This study aims to clarify the efficacy and mechanism of DHA in the treatment of CBP and its effect on the accumulation of BMMSCs. The experimental CBP was produced in C57BL/6 male mice via intraurethrally administered

Identifiers

PMID34956376
PMCPMC8694990
OpenAlexW4200200623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.